ID   HT29 LM1
AC   CVCL_5U94
DR   cancercelllines; CVCL_5U94
DR   Wikidata; Q54896581
RX   PubMed=24823486;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0320 ! HT-29
SX   Female
AG   44Y
CA   Cancer cell line
DT   Created: 23-02-16; Last updated: 19-12-24; Version: 18
CH   CVCL_5U95 ! HT29 LM2
//
RX   PubMed=24823486; DOI=10.1371/journal.pone.0097432; PMCID=PMC4019574;
RA   Elliott, Victoria A.
RA   Rychahou, Piotr
RA   Zaytseva, Yekaterina Y.
RA   Evers, B. Mark
RT   "Activation of c-Met and upregulation of CD44 expression are
RT   associated with the metastatic phenotype in the colorectal cancer
RT   liver metastasis model.";
RL   PLoS ONE 9:e97432.1-e97432.8(2014).
//