ID   UCW 113
AC   CVCL_5T99
DR   Wikidata; Q54990075
RX   PubMed=6965094;
RX   PubMed=7193212;
RX   PubMed=7444715;
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_2234 ! V79
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 23-02-16; Last updated: 29-06-23; Version: 9
//
RX   PubMed=6965094; DOI=10.1128/mcb.1.1.58-65.1981;
RA   Wasmuth J.J., Hill J.M., Vock L.S.;
RT   "Identification and characterization of a third complementation group
RT   of emetine-resistant Chinese hamster cell mutants.";
RL   Mol. Cell. Biol. 1:58-65(1981).
//
RX   PubMed=7193212; DOI=10.1083/jcb.87.3.697;
RA   Wasmuth J.J., Chu L.-Y.;
RT   "Linkage in cultured Chinese hamster cells of two genes, emtB and
RT   leuS, involved in protein synthesis and isolation of cell lines with
RT   mutations in three linked genes.";
RL   J. Cell Biol. 87:697-702(1980).
//
RX   PubMed=7444715; DOI=10.1007/BF01539152;
RA   Wasmuth J.J., Hill J.M., Vock L.S.;
RT   "Biochemical and genetic evidence for a new class of emetine-resistant
RT   Chinese hamster cells with alterations in the protein biosynthetic
RT   machinery.";
RL   Somatic Cell Genet. 6:495-516(1980).
//