ID   RJK526
AC   CVCL_5A68
SY   Clone 526; 526
DR   Wikidata; Q54950522
RX   PubMed=1170021;
RX   PubMed=6877239;
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_5A61 ! V79 A3
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-12-15; Last updated: 29-06-23; Version: 9
//
RX   PubMed=1170021; DOI=10.1016/0092-8674(75)90019-7;
RA   Fenwick R.G. Jr., Caskey C.T.;
RT   "Mutant Chinese hamster cells with a thermosensitive
RT   hypoxanthine-guanine phosphoribosyltransferase.";
RL   Cell 5:115-122(1975).
//
RX   PubMed=6877239; DOI=10.1128/mcb.3.6.1086-1096.1983;
RA   Fuscoe J.C., Fenwick R.G. Jr., Ledbetter D.H., Caskey C.T.;
RT   "Deletion and amplification of the HGPRT locus in Chinese hamster
RT   cells.";
RL   Mol. Cell. Biol. 3:1086-1096(1983).
//