ID   CHO-xrs-4
AC   CVCL_5A39
SY   xrs-4; xrs4
DR   Wikidata; Q54813130
RX   PubMed=2564870;
RX   PubMed=6197643;
RX   PubMed=6513971;
RX   PubMed=9032253;
CC   Characteristics: Sensitive to X-ray. Has a defect in double-strand break rejoining (PubMed=6513971).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-12-15; Last updated: 19-12-24; Version: 8
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RX   PubMed=2564870; DOI=10.1080/09553008914550651;
RA   Denekamp J., Whitmore G.F., Jeggo P.A.;
RT   "Biphasic survival curves for XRS radiosensitive cells: subpopulations
RT   or transient expression of repair competence?";
RL   Int. J. Radiat. Biol. 55:605-617(1989).
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RX   PubMed=6197643; DOI=10.1016/0167-8817(83)90026-3;
RA   Jeggo P.A., Kemp L.M.;
RT   "X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation
RT   and cross-sensitivity to other DNA-damaging agents.";
RL   Mutat. Res. 112:313-327(1983).
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RX   PubMed=6513971; DOI=10.1016/0167-8817(84)90037-3;
RA   Kemp L.M., Sedgwick S.G., Jeggo P.A.;
RT   "X-ray sensitive mutants of Chinese hamster ovary cells defective in
RT   double-strand break rejoining.";
RL   Mutat. Res. 132:189-196(1984).
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RX   PubMed=9032253; DOI=10.1128/mcb.17.3.1264; PMCID=PMC231851;
RA   Singleton B.K., Priestley A., Steingrimsdottir H., Gell D., Blunt T.,
RA   Jackson S.P., Lehmann A.R., Jeggo P.A.;
RT   "Molecular and biochemical characterization of xrs mutants defective
RT   in Ku80.";
RL   Mol. Cell. Biol. 17:1264-1273(1997).
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