ID   COMMA-D
AC   CVCL_5731
SY   Comma-D; COMMA D; Comma 1D; Comma-1D; COMMA-1D; COMMA1D; CD
DR   EFO; EFO_0022829
DR   GEO; GSE182589
DR   Wikidata; Q54814228
RX   PubMed=2423737;
RX   PubMed=3653254;
RX   PubMed=6587390;
RX   PubMed=24259225;
RX   PubMed=36630696;
CC   Characteristics: Can functionally differentiate to preneoplastic and neoplastic phenotypes (PubMed=36630696).
CC   Omics: Transcriptomics; RNAseq; Single cell.
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
CC   Breed/subspecies: BALB/c.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   1Y
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 16
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RX   PubMed=2423737; DOI=10.1093/jnci/76.6.1143;
RA   Medina D., Oborn C.J., Kittrell F.S., Ullrich R.L.;
RT   "Properties of mouse mammary epithelial cell lines characterized by in
RT   vivo transplantation and in vitro immunocytochemical methods.";
RL   J. Natl. Cancer Inst. 76:1143-1156(1986).
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RX   PubMed=3653254; DOI=10.1016/0014-4827(87)90105-4;
RA   Medina D., Li M.-L., Oborn C.J., Bissell M.J.;
RT   "Casein gene expression in mouse mammary epithelial cell lines:
RT   dependence upon extracellular matrix and cell type.";
RL   Exp. Cell Res. 172:192-203(1987).
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RX   PubMed=6587390; DOI=10.1073/pnas.81.12.3756; PMCID=PMC345298;
RA   Danielson K.G., Oborn C.J., Durban E.M., Butel J.S., Medina D.;
RT   "Epithelial mouse mammary cell line exhibiting normal morphogenesis in
RT   vivo and functional differentiation in vitro.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:3756-3760(1984).
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RX   PubMed=24259225; DOI=10.1007/BF02917600;
RA   Medina D., Morrison D., Oborn C.J.;
RT   "Selenium retention and inhibition of cell growth in mouse mammary
RT   epithelial cell lines in vitro.";
RL   Biol. Trace Elem. Res. 8:19-35(1985).
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RX   PubMed=36630696; DOI=10.3389/fgene.2022.894597; PMCID=PMC9237515;
RA   Dave A., Nekritz E., Charytonowicz D., Beaumont M., Smith M.,
RA   Beaumont K.G., Silva J., Sebra R.P.;
RT   "Integration of single-cell transcriptomics with a high throughput
RT   functional screening assay to resolve cell type, growth kinetics, and
RT   stemness heterogeneity within the Comma-1D cell line.";
RL   Front. Genet. 13:894597.1-894597.20(2022).
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