ID   NALM-30
AC   CVCL_5668
SY   NALM30
DR   ArrayExpress; E-MTAB-11038
DR   ArrayExpress; E-MTAB-11039
DR   Cosmic; 999735
DR   Cosmic; 2491086
DR   JCRB; JCRB1858
DR   Wikidata; Q54907412
RX   PubMed=9067587;
RX   PubMed=9680106;
RX   PubMed=10363160;
RX   PubMed=10576511;
RX   PubMed=34940123;
CC   Population: Japanese.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=34940123).
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=10363160; PubMed=10576511).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
ST   Source(s): JCRB=JCRB1858
ST   Amelogenin: X,Y
ST   CSF1PO: 7,12
ST   D13S317: 8
ST   D16S539: 9
ST   D5S818: 11,13
ST   D7S820: 8,11
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 17,18
DI   NCIt; C82192; Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
DI   ORDO; Orphanet_589534; Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_5665 ! NALM-27
OI   CVCL_5666 ! NALM-28
OI   CVCL_5669 ! NALM-31
OI   CVCL_5670 ! NALM-32
SX   Male
AG   39Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 18
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RX   PubMed=9067587; DOI=10.1038/sj.leu.2400571;
RA   Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A.,
RA   Janssen J.W.G., Drexler H.G.;
RT   "Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in
RT   human early B-lineage leukemia cell lines.";
RL   Leukemia 11:441-447(1997).
//
RX   PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2;
RA   Matsuo Y., Drexler H.G.;
RT   "Establishment and characterization of human B cell precursor-leukemia
RT   cell lines.";
RL   Leuk. Res. 22:567-579(1998).
//
RX   PubMed=10363160;
RA   Matsuo Y., Sugimoto A., Harashima A., Nishizaki C., Drexler H.G.,
RA   Orita K.;
RT   "Myeloperoxidase positive acute lymphoblastic leukemia cell lines,
RT   NALM-30, NALM-31 and NALM-32, carrying Philadelphia chromosome with
RT   biphenotypic characteristics.";
RL   Hum. Cell 11:221-230(1998).
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RX   PubMed=10576511; DOI=10.1016/s0145-2126(99)00131-9;
RA   Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.;
RT   "ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
RL   Leuk. Res. 23:1055-1060(1999).
//
RX   PubMed=34940123; DOI=10.3390/cimb43030149;
RA   Quentmeier H., Pommerenke C., Drexler H.G.;
RT   "Molecular genetics of pre-B acute lymphoblastic leukemia sister cell
RT   lines during disease progression.";
RL   Curr. Issues Mol. Biol. 43:2147-2156(2021).
//