ID   TKC2
AC   CVCL_5597
SY   TKC-2
DR   JCRB; IFO50373
DR   TKG; TKG 0354
DR   Wikidata; Q54972577
RX   PubMed=1663919;
RX   PubMed=7641784;
RX   PubMed=9224657;
RX   PubMed=11520047;
RX   PubMed=17233813;
CC   Doubling time: ~27 hours (Note=Lot 04192002) (JCRB=IFO50373).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Kidney, renal tubule; UBERON=UBERON_0009773.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   2M
CA   Conditionally immortalized cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 13
//
RX   PubMed=1663919; DOI=10.1111/j.1349-7006.1991.tb01803.x; PMCID=PMC5918353;
RA   Yanai N., Satoh T., Kyo S., Abe K., Suzuki M., Obinata M.;
RT   "A tubule cell line established from transgenic mice harboring
RT   temperature-sensitive simian virus 40 large T-antigen gene.";
RL   Jpn. J. Cancer Res. 82:1344-1348(1991).
//
RX   PubMed=7641784; DOI=10.1006/excr.1995.1236;
RA   Taher A., Yanai N., Obinata M.;
RT   "Properties of incompletely immortalized cell lines generated from a
RT   line established from temperature-sensitive SV40 T-antigen gene
RT   transgenic mice.";
RL   Exp. Cell Res. 219:332-338(1995).
//
RX   PubMed=9224657; DOI=10.1046/j.1365-2443.1997.1160314.x;
RA   Obinata M.;
RT   "Conditionally immortalized cell lines with differentiated functions
RT   established from temperature-sensitive T-antigen transgenic mice.";
RL   Genes Cells 2:235-244(1997).
//
RX   PubMed=11520047; DOI=10.1006/bbrc.2001.5247;
RA   Obinata M.;
RT   "Possible applications of conditionally immortalized tissue cell lines
RT   with differentiation functions.";
RL   Biochem. Biophys. Res. Commun. 286:667-672(2001).
//
RX   PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456;
RA   Obinata M.;
RT   "The immortalized cell lines with differentiation potentials: their
RT   establishment and possible application.";
RL   Cancer Sci. 98:275-283(2007).
//