ID   RL-34
AC   CVCL_5583
SY   RL34; Rat Liver-34
DR   JCRB; JCRB0247
DR   Wikidata; Q54950579
RX   DOI=10.11418/jtca1981.15.2_141;
RX   PubMed=137072;
RX   PubMed=282624;
RX   PubMed=3552263;
RX   PubMed=6244092;
CC   Doubling time: ~1 day (Note=Lot 03022017) (JCRB=JCRB0247).
CC   Sequence variation: Mutation; RGD; 3889; Tp53; Unexplicit; TC->GA in 3'splicing signal of intron 4; Zygosity=Unspecified (DOI=10.11418/jtca1981.15.2_141).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Breed/subspecies: Wistar; RS=RS_0000955.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
AG   7D
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 13
//
RX   DOI=10.11418/jtca1981.15.2_141;
RA   Miyamura Y., Moritoh C., Ishii N., Okigaki T.;
RT   "p53 gene mutations in the immortalized rat epithelial cell lines.";
RL   Tissue Cult. Res. Commun. 15:141-145(1996).
//
RX   PubMed=137072;
RA   Karasaki S., Okigaki T.;
RT   "Surface membrane nucleoside triphosphatase activity and
RT   tumorigenicity of cultured liver epithelial cells.";
RL   Cancer Res. 36:4491-4499(1976).
//
RX   PubMed=282624; DOI=10.1073/pnas.75.12.6069; PMCID=PMC393119;
RA   Swierenga S.H.H., Whitfield J.F., Karasaki S.;
RT   "Loss of proliferative calcium dependence: simple in vitro indicator
RT   of tumorigenicity.";
RL   Proc. Natl. Acad. Sci. U.S.A. 75:6069-6072(1978).
//
RX   PubMed=3552263; DOI=10.1247/csf.12.53;
RA   Yamada M., Okigaki T., Awai M.;
RT   "Adhesion and growth of rat liver epithelial cells on an extracellular
RT   matrix with proteins from fibroblast conditioned medium.";
RL   Cell Struct. Funct. 12:53-62(1987).
//
RX   PubMed=6244092;
RA   Karasaki S., Suh M.H., Salas M., Raymond J.;
RT   "Cell surface adenosine 5'-triphosphatase as an in vitro marker of the
RT   lineage and cytodifferentiation of oncogenic epithelial cells from rat
RT   liver parenchyma.";
RL   Cancer Res. 40:1318-1328(1980).
//