ID   BEL-7402
AC   CVCL_5492
SY   Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402
DR   BTO; BTO_0004050
DR   EFO; EFO_0022709
DR   ChEMBL-Cells; CHEMBL3307770
DR   ChEMBL-Targets; CHEMBL614279
DR   Cosmic; 1499247
DR   Cosmic; 2773179
DR   GEO; GSM936754
DR   GEO; GSM1374400
DR   PRIDE; PXD015917
DR   PubChem_Cell_line; CVCL_5492
DR   TOKU-E; 3571
DR   Wikidata; Q54795968
RX   DOI=10.1007/978-4-431-68349-0_4;
RX   PubMed=1849045;
RX   PubMed=6154311;
RX   PubMed=6275024;
RX   PubMed=14571772;
RX   PubMed=23167424;
RX   PubMed=23505090;
RX   PubMed=28807831;
WW   Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=28807831). Originally thought to originate from a 53 year old male patient with a hepatocellular carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00549.
CC   Population: African American.
CC   Doubling time: 20 hours (PubMed=6154311); 31.2 +- 1.1 hours (PubMed=23167424).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Proteomics; Quantitative.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3131C0001000700010, 3142C0001000000035). They were the sole source for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 12
ST   D7S820: 12
ST   D8S1179: 12
ST   FGA: 18,21
ST   TH01: 7
ST   TPOX: 12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 32
CH   CVCL_5493 ! BEL-7402/5-FU
CH   CVCL_M184 ! BEL-7402/5'-DFUR
CH   CVCL_D8ER ! Ubigene BEL-7402 KLF14 KO
//
RX   PubMed=14571772;
RA   Liu, Lian-Xin
RA   Jiang, Hong-Chi
RA   Liu, Zhi-Hua
RA   Zhu, An-Long
RA   Zhou, Jing
RA   Zhang, Wei-Hui
RA   Wang, Xiu-Qin
RA   Wu, Min
RT   "Gene expression profiles of hepatoma cell line BEL-7402.";
RL   Hepato-Gastroenterol. 50:1496-1501(2003).
//
RX   PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002;
RA   Rebouissou, Sandra
RA   Zucman-Rossi, Jessica
RA   Moreau, Richard
RA   Qiu, Zhi-Xin
RA   Hui, Li-Jian
RT   "Note of caution: contaminations of hepatocellular cell lines.";
RL   J. Hepatol. 67:896-897(2017).
//
RX   PubMed=6154311; DOI=10.1360/ya1980-23-2-236;
RA   Chen, Rui-Ming
RA   Zhu, De-Hou
RA   Ye, Xiu-Zhen
RA   Shen, Ding-Wu
RA   Lu, Rong-Hua
RT   "Establishment of three human liver carcinoma cell lines and some of
RT   their biological characteristics in vitro.";
RL   Sci. Sin. 23:236-247(1980).
//
RX   PubMed=6275024; DOI=10.1099/0022-1317-57-1-95;
RA   Koshy, Rajen
RA   Maupas, Philippe
RA   Muller, R.
RA   Hofschneider, Peter Hans
RT   "Detection of hepatitis B virus-specific DNA in the genomes of human
RT   hepatocellular carcinoma and liver cirrhosis tissues.";
RL   J. Gen. Virol. 57:95-102(1981).
//
RX   PubMed=23505090; DOI=10.1002/hep.26402;
RA   Wang, Kai
RA   Lim, Ho Yeong
RA   Shi, Stephanie
RA   Lee, Jeeyun
RA   Deng, Shi-Bing
RA   Xie, Tao
RA   Zhu, Zhou
RA   Wang, Yu-Li
RA   Pocalyko, David
RA   Yang, Wei Jennifer
RA   Rejto, Paul A.
RA   Mao, Mao
RA   Park, Cheol-Keun
RA   Xu, Jiang-Chun
RT   "Genomic landscape of copy number aberrations enables the
RT   identification of oncogenic drivers in hepatocellular carcinoma.";
RL   Hepatology 58:706-717(2013).
//
RX   PubMed=23167424; DOI=10.7314/APJCP.2012.13.9.4807;
RA   Gu, Wei
RA   Fang, Fan-Fu
RA   Li, Bai
RA   Cheng, Bin-Bin
RA   Ling, Chang-Quan
RT   "Characterization and resistance mechanisms of a
RT   5-fluorouracil-resistant hepatocellular carcinoma cell line.";
RL   Asian Pac. J. Cancer Prev. 13:4807-4814(2012).
//
RX   DOI=10.1007/978-4-431-68349-0_4;
RA   Alexander, Jennifer J.
RT   "Human hepatoma cell lines.";
RL   (In book chapter) Neoplasms of the liver; Okuda, Kunio & Ishak, Kamal George (eds.); pp.47-56; Springer; Tokyo; Japan (1987).
//
RX   PubMed=1849045;
RA   Fuhrer, J. Peter
RA   Xie, Hong
RA   Murphy, Martin J. Jr.
RA   Ye, Jian-Nan
RA   Yao, Zhen
RT   "Characterization of a membrane-associated glycoprotein (gp 43) on
RT   human hepatocellular carcinoma by a monoclonal antibody.";
RL   Cancer Res. 51:2158-2163(1991).
//