ID   VACO 9P
AC   CVCL_5413
AS   CVCL_A437
SY   Vaco 9P; VACO9P; V9P
DR   cancercelllines; CVCL_5413
DR   ColonAtlas; V9P
DR   Cosmic; 711267
DR   Cosmic; 887233
DR   Cosmic; 1132562
DR   Cosmic; 1479634
DR   GEO; GSM2550021
DR   IARC_TP53; 6485
DR   Wikidata; Q54992840
RX   PubMed=3349466;
RX   PubMed=6498841;
RX   PubMed=9000147;
RX   PubMed=9000572;
RX   PubMed=11526487;
RX   PubMed=20570890;
RX   PubMed=24042735;
RX   PubMed=28683746;
CC   Doubling time: 110 hours (PubMed=6498841).
CC   Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=28683746).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly245Asp (c.734G>A); ClinVar=VCV000012355; Zygosity=Homozygous (PubMed=9000147; PubMed=24042735; PubMed=28683746).
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: STR profile mentioned but not shown in PubMed=24042735; obtained by personal communication of Lind G.E.
CC   Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
ST   Source(s): PubMed=24042735
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 9,12
ST   D16S539: 12,13
ST   D18S51: 13
ST   D19S433: 13
ST   D21S11: 30
ST   D2S1338: 17,20
ST   D3S1358: 13,15
ST   D5S818: 12
ST   D7S820: 10
ST   D8S1179: 13,14
ST   FGA: 23,25
ST   TH01: 6,9.3
ST   TPOX: 8,12
ST   vWA: 19
DI   NCIt; C9383; Rectal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_5412 ! VACO 9M
SX   Male
AG   67Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 21
//
RX   PubMed=3349466;
RA   Chantret I., Barbat A., Dussaulx E., Brattain M.G., Zweibaum A.;
RT   "Epithelial polarity, villin expression, and enterocytic
RT   differentiation of cultured human colon carcinoma cells: a survey of
RT   twenty cell lines.";
RL   Cancer Res. 48:1936-1942(1988).
//
RX   PubMed=6498841;
RA   McBain J.A., Weese J.L., Meisner L.F., Wolberg W.H., Willson J.K.V.;
RT   "Establishment and characterization of human colorectal cancer cell
RT   lines.";
RL   Cancer Res. 44:5813-5821(1984).
//
RX   PubMed=9000147;
RA   Cottu P.-H., Muzeau F., Estreicher A., Flejou J.-F., Iggo R.D.,
RA   Thomas G., Hamelin R.;
RT   "Inverse correlation between RER+ status and p53 mutation in
RT   colorectal cancer cell lines.";
RL   Oncogene 13:2727-2730(1996).
//
RX   PubMed=9000572;
RA   Hoang J.-M., Cottu P.-H., Thuille B., Salmon R.J., Thomas G.,
RA   Hamelin R.;
RT   "BAT-26, an indicator of the replication error phenotype in colorectal
RT   cancers and cell lines.";
RL   Cancer Res. 57:300-303(1997).
//
RX   PubMed=11526487; DOI=10.1038/sj.onc.1204611;
RA   Gayet J., Zhou X.-P., Duval A., Rolland S., Hoang J.-M., Cottu P.-H.,
RA   Hamelin R.;
RT   "Extensive characterization of genetic alterations in a series of
RT   human colorectal cancer cell lines.";
RL   Oncogene 20:5025-5032(2001).
//
RX   PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192;
RA   Janakiraman M., Vakiani E., Zeng Z.-S., Pratilas C.A., Taylor B.S.,
RA   Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C.M.,
RA   Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M.,
RA   Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.;
RT   "Genomic and biological characterization of exon 4 KRAS mutations in
RT   human cancer.";
RL   Cancer Res. 70:5901-5911(2010).
//
RX   PubMed=24042735; DOI=10.1038/oncsis.2013.35;
RA   Ahmed D., Eide P.W., Eilertsen I.A., Danielsen S.A., Eknaes M.,
RA   Hektoen M., Lind G.E., Lothe R.A.;
RT   "Epigenetic and genetic features of 24 colon cancer cell lines.";
RL   Oncogenesis 2:e71.1-e71.8(2013).
//
RX   PubMed=28683746; DOI=10.1186/s12943-017-0691-y;
RA   Berg K.C.G., Eide P.W., Eilertsen I.A., Johannessen B., Bruun J.,
RA   Danielsen S.A., Bjornslett M., Meza-Zepeda L.A., Eknaes M., Lind G.E.,
RA   Myklebost O., Skotheim R.I., Sveen A., Lothe R.A.;
RT   "Multi-omics of 34 colorectal cancer cell lines -- a resource for
RT   biomedical studies.";
RL   Mol. Cancer 16:116.1-116.16(2017).
//