ID   VACO 429
AC   CVCL_5401
SY   Vaco 429; VACO-429; Vaco-429; VACO429; V429
DR   cancercelllines; CVCL_5401
DR   Cosmic; 1312320
DR   GEO; GSM784051
DR   IARC_TP53; 21753
DR   Progenetix; CVCL_5401
DR   Wikidata; Q54992732
RX   PubMed=7816807;
RX   PubMed=8385345;
RX   PubMed=15162061;
RX   PubMed=16418264;
RX   PubMed=20606684;
WW   https://www.cellosaurus.org/pawefish/ColonCellLineDescriptions/VACO429.html
CC   Sequence variation: Mutation; HGNC; 1148; BUB1; Simple; p.Ser492Tyr (c.1542C>A); ClinVar=VCV000007083; Zygosity=Unspecified (PubMed=15162061).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Heterozygous (PubMed=16418264).
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
//
RX   PubMed=7816807; DOI=10.1073/pnas.92.1.151;
RA   Lisitsyn N.A., Lisitsina N.M., Dalbagni G., Barker P., Sanchez C.A.,
RA   Gnarra J.R., Linehan W.M., Reid B.J., Wigler M.H.;
RT   "Comparative genomic analysis of tumors: detection of DNA losses and
RT   amplification.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:151-155(1995).
//
RX   PubMed=8385345; DOI=10.1073/pnas.90.7.2846;
RA   Smith K.J., Johnson K.A., Bryan T.M., Hill D.E., Markowitz S.D.,
RA   Willson J.K.V., Paraskeva C., Petersen G.M., Hamilton S.R.,
RA   Vogelstein B., Kinzler K.W.;
RT   "The APC gene product in normal and tumor cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:2846-2850(1993).
//
RX   PubMed=15162061; DOI=10.1159/000077512;
RA   Grigorova M., Staines J.M., Ozdag H., Caldas C., Edwards P.A.W.;
RT   "Possible causes of chromosome instability: comparison of chromosomal
RT   abnormalities in cancer cell lines with mutations in BRCA1, BRCA2,
RT   CHK2 and BUB1.";
RL   Cytogenet. Genome Res. 104:333-340(2004).
//
RX   PubMed=16418264; DOI=10.1073/pnas.0510146103;
RA   Liu Y., Bodmer W.F.;
RT   "Analysis of P53 mutations and their expression in 56 colorectal
RT   cancer cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:976-981(2006).
//
RX   PubMed=20606684; DOI=10.1038/sj.bjc.6605780;
RA   Bracht K., Nicholls A.M., Liu Y., Bodmer W.F.;
RT   "5-fluorouracil response in a large panel of colorectal cancer cell
RT   lines is associated with mismatch repair deficiency.";
RL   Br. J. Cancer 103:340-346(2010).
//