ID   KPMM2
AC   CVCL_5311
SY   KPMM-2
DR   Wikidata; Q54900441
RX   DOI=10.1007/0-306-46877-8_4;
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=7723407;
RX   PubMed=8797890;
RX   PubMed=10936422;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=KPMM2
WW   Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
CC   Population: Japanese.
CC   Characteristics: Produces IgG lambda.
CC   Characteristics: IL6 dependent.
CC   Doubling time: ~48 hours (Note=With IL6), ~72 hours (Note=Without IL6) (PubMed=7723407).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   77Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 18
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RX   DOI=10.1007/0-306-46877-8_4;
RA   Jernberg-Wiklund H., Nilsson K.;
RT   "Multiple myeloma cell lines.";
RL   (In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000).
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RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
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RX   PubMed=7723407;
RA   Goto H., Shimazaki C., Tatsumi T., Yamagata N., Fujita N.,
RA   Tsuchiya M., Koishihara Y., Ohsugi Y., Nakagawa M.;
RT   "Establishment of a novel myeloma cell line KPMM2 carrying
RT   t(3;14)(q21;q32), which proliferates specifically in response to
RT   interleukin-6 through an autocrine mechanism.";
RL   Leukemia 9:711-718(1995).
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RX   PubMed=8797890; DOI=10.1111/j.1349-7006.1996.tb02108.x; PMCID=PMC5921175;
RA   Tatsumi T., Shimazaki C., Goto H., Araki S.-i., Sudo Y., Yamagata N.,
RA   Ashihara E., Inaba T., Fujita N., Nakagawa M.;
RT   "Expression of adhesion molecules on myeloma cells.";
RL   Jpn. J. Cancer Res. 87:837-842(1996).
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RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler H.G., Matsuo Y.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
//