ID ACC-MESO-1 AC CVCL_5113 SY ACC-Meso-1; ACCMESO1; MESO-1 DR CLO; CLO_0050082 DR ArrayExpress; E-MTAB-2770 DR BioSample; SAMN03471958 DR BioSample; SAMN10987705 DR cancercelllines; CVCL_5113 DR Cell_Model_Passport; SIDM01526 DR Cosmic; 877273 DR Cosmic; 1481540 DR Cosmic; 2759002 DR Cosmic; 2759214 DR DepMap; ACH-000086 DR FANTOM5_SSTAR; 10493-107B7 DR GEO; GSM551967 DR GEO; GSM850296 DR GEO; GSM886862 DR GEO; GSM887927 DR IARC_TP53; 24548 DR IARC_TP53; 30221 DR LiGeA; CCLE_096 DR PharmacoDB; ACCMESO1_52_2019 DR Progenetix; CVCL_5113 DR RCB; RCB2292 DR Wikidata; Q54608242 RX PubMed=16630136; RX PubMed=17270034; RX PubMed=21245096; RX PubMed=22460905; RX PubMed=25902174; RX PubMed=26011428; RX PubMed=26589293; RX PubMed=28553954; RX PubMed=30894373; RX PubMed=31068700; CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Population: Japanese. CC HLA typing: A*31:01,31:01; B*15:01,46:01; C*15:02,15:02 (PubMed=26589293). CC Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=16630136). CC Sequence variation: Mutation; HGNC; HGNC:7773; NF2; Simple; p.Gln389Ter (c.1165C>T); Zygosity=Homozygous (PubMed=16630136; DepMap=ACH-000086). CC Omics: Genomics; Whole exome sequencing. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=1.98%; Native American=0.64%; East Asian, North=84.83%; East Asian, South=11.7%; South Asian=0%; European, North=0%; European, South=0.85% (PubMed=30894373). CC Donor information: No history of asbestos exposure (PubMed=16630136). CC Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977. ST Source(s): RCB=RCB2292 ST Amelogenin: X ST CSF1PO: 10 ST D13S317: 8 ST D16S539: 12 ST D5S818: 12 ST D7S820: 10,12 ST TH01: 9 ST TPOX: 11 ST vWA: 17 DI NCIt; C45662; Pleural epithelioid mesothelioma DI ORDO; Orphanet_50251; Pleural mesothelioma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Female AG 61Y CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 30 // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=28553954; DOI=10.1038/onc.2017.147; RA Kato, Taketo RA Sato, Tatsuhiro RA Yokoi, Kohei RA Sekido, Yoshitaka RT "E-cadherin expression is correlated with focal adhesion kinase RT inhibitor resistance in merlin-negative malignant mesothelioma RT cells."; RL Oncogene 36:5522-5531(2017). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387; RA Hakiri, Shuhei RA Osada, Hirotaka RA Ishiguro, Futoshi RA Murakami, Hideki RA Murakami-Tonami, Yuko RA Yokoi, Kohei RA Sekido, Yoshitaka RT "Functional differences between wild-type and mutant-type RT BRCA1-associated protein 1 tumor suppressor against malignant RT mesothelioma cells."; RL Cancer Sci. 106:990-999(2015). // RX PubMed=16630136; DOI=10.1111/j.1349-7006.2006.00184.x; PMCID=PMC11158456; RA Usami, Noriyasu RA Fukui, Takayuki RA Kondo, Masashi RA Taniguchi, Tetsuo RA Yokoyama, Toshihiko RA Mori, Shoichi RA Yokoi, Kohei RA Horio, Yoshitsugu RA Shimokata, Kaoru RA Sekido, Yoshitaka RA Hida, Toyoaki RT "Establishment and characterization of four malignant pleural RT mesothelioma cell lines from Japanese patients."; RL Cancer Sci. 97:387-394(2006). // RX PubMed=17270034; DOI=10.1111/j.1349-7006.2006.00386.x; PMCID=PMC11158069; RA Taniguchi, Tetsuo RA Karnan, Sivasundaram RA Fukui, Takayuki RA Yokoyama, Toshihiko RA Tagawa, Hiroyuki RA Yokoi, Kohei RA Ueda, Yuichi RA Mitsudomi, Tetsuya RA Horio, Yoshitsugu RA Hida, Toyoaki RA Yatabe, Yasushi RA Seto, Masao RA Sekido, Yoshitaka RT "Genomic profiling of malignant pleural mesothelioma with array-based RT comparative genomic hybridization shows frequent non-random RT chromosomal alteration regions including JUN amplification on 1p32."; RL Cancer Sci. 98:438-446(2007). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164; RA Murakami, Hideki RA Mizuno, Tetsuya RA Taniguchi, Tetsuo RA Fujii, Makiko RA Ishiguro, Futoshi RA Fukui, Takayuki RA Akatsuka, Shinya RA Horio, Yoshitsugu RA Hida, Toyoaki RA Kondo, Yutaka RA Toyokuni, Shinya RA Osada, Hirotaka RA Sekido, Yoshitaka RT "LATS2 is a tumor suppressor gene of malignant mesothelioma."; RL Cancer Res. 71:873-883(2011). // RX PubMed=25902174; DOI=10.1097/JTO.0000000000000493; RA Miyanaga, Akihiko RA Masuda, Mari RA Tsuta, Koji RA Kawasaki, Kumiko RA Nakamura, Yuka RA Sakuma, Tomohiro RA Asamura, Hisao RA Gemma, Akihiko RA Yamada, Tesshi RT "Hippo pathway gene mutations in malignant mesothelioma: revealed by RT RNA and targeted exon sequencing."; RL J. Thorac. Oncol. 10:844-851(2015). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). //