ID SNU-308 AC CVCL_5048 SY SNU308; NCI-SNU-308 DR ArrayExpress; E-MTAB-2770 DR BioSample; SAMN10988081 DR cancercelllines; CVCL_5048 DR Cell_Model_Passport; SIDM00161 DR ChEMBL-Cells; CHEMBL3307456 DR ChEMBL-Targets; CHEMBL614932 DR Cosmic; 738869 DR Cosmic; 2674056 DR DepMap; ACH-000141 DR GEO; GSM887620 DR GEO; GSM888704 DR IARC_TP53; 28334 DR KCLB; 00308 DR LiGeA; CCLE_685 DR PharmacoDB; SNU308_1454_2019 DR Progenetix; CVCL_5048 DR PubChem_Cell_line; CVCL_5048 DR Wikidata; Q54955169 RX CelloPub=CLPUB00275; RX PubMed=12107841; RX PubMed=19956504; RX PubMed=22460905; RX PubMed=26589293; RX PubMed=27231123; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=32899426; RX PubMed=39026794; CC Part of: Biliary tract cancer cell line atlas. CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: Seoul National University (SNU) cell line collection. CC Population: Korean. CC Doubling time: 48 hours (PubMed=12107841). CC HLA typing: A*24:02,33:03; B*48:01,58:01; C*03:02,08:03 (PubMed=26589293). CC Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val217Gly (c.650T>G); Zygosity=Homozygous (DepMap=ACH-000141). CC Omics: Genomics; Whole exome sequencing. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0.26%; Native American=0%; East Asian, North=62.71%; East Asian, South=35.2%; South Asian=0%; European, North=0%; European, South=1.83% (PubMed=30894373). CC Derived from site: In situ; Gallbladder; UBERON=UBERON_0002110. ST Source(s): KCLB=00308 ST Amelogenin: X ST CSF1PO: 12 ST D13S317: 8 ST D3S1358: 16 ST D5S818: 9 ST D7S820: 7,12 ST FGA: 25,26 ST TH01: 8 ST TPOX: 8 ST vWA: 16 DI NCIt; C3844; Gallbladder carcinoma DI ORDO; Orphanet_56044; Carcinoma of gallbladder and extrahepatic biliary tract OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Sex unspecified AG Age unspecified CA Cancer cell line DT Created: 04-04-12; Last updated: 10-04-25; Version: 30 // RX PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737; RA Saha, Supriya Kumar RA Gordan, John D. RA Kleinstiver, Benjamin P. RA Vu, Phuong RA Najem, Mortada S. RA Yeo, Jia-Chi RA Shi, Lei RA Kato, Yasutaka RA Levin, Rebecca S. RA Webber, James T. RA Damon, Leah J. RA Egan, Regina K. RA Greninger, Patricia RA McDermott, Ultan RA Garnett, Mathew J. RA Jenkins, Roger L. RA Rieger-Christ, Kimberly M. RA Sullivan, Travis B. RA Hezel, Aram Francis RA Liss, Andrew S. RA Mizukami, Yusuke RA Goyal, Lipika RA Ferrone, Cristina Rosa RA Zhu, Andrew Xiu-Xuan RA Joung, Jae Keith RA Shokat, Kevan Michael RA Benes, Cyril Henri RA Bardeesy, Nabeel M. RT "Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity RT and SRC dependence in intrahepatic cholangiocarcinoma."; RL Cancer Discov. 6:727-739(2016). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=12107841; DOI=10.1038/sj.bjc.6600440; PMCID=PMC2376107; RA Ku, Ja-Lok RA Yoon, Kyong-Ah RA Kim, Il-Jin RA Kim, Woo-Ho RA Jang, Jin-Young RA Suh, Kyung-Suk RA Kim, Sun-Whe RA Park, Yong-Hyun RA Hwang, Jae-Ho RA Yoon, Yong-Bum RA Park, Jae-Gahb RT "Establishment and characterisation of six human biliary tract cancer RT cell lines."; RL Br. J. Cancer 87:187-193(2002). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=32899426; DOI=10.3390/cancers12092510; PMCID=PMC7565451; RA Scherer, Dominique RA Davila-Lopez, Marcela RA Goeppert, Benjamin RA Abrahamsson, Sanna RA Gonzalez Silos, Rosa RA Nova, Igor RA Marcelain, Katherine RA Roa, Juan Carlos RA Ibberson, David RA Umu, Sinan U. RA Rounge, Trine Ballestad RA Roessler, Stephanie RA Lorenzo-Bermejo, Justo RT "RNA sequencing of hepatobiliary cancer cell lines: data and RT applications to mutational and transcriptomic profiling."; RL Cancers (Basel) 12:2510.1-2510.14(2020). // RX PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448; RA Vijay, Vindhya RA Karisani, Negin RA Shi, Lei RA Hung, Yu-Han RA Vu, Phuong RA Kattel, Prabhat RA Kenney, Lauren RA Merritt, Joshua RA Adil, Ramzi RA Wu, Qi-Biao RA Zhen, Yuan-Li RA Morris, Robert RA Kreuzer, Johannes RA Kathiresan, Meena RA Herrera Lopez, Xcanda Ixchel RA Ellis, Haley RA Gritti, Ilaria G. RA Lecorgne, Lilian RA Farag, Ines RA Popa, Alexandra RA Shen, William RA Kato, Hiroyuki RA Xu, Qin RA Balasooriya, Eranga Roshan RA Wu, Meng-Ju RA Chaturantabut, Saireudee RA Kelley, Robin Kate RA Cleary, James Mark RA Lawrence, Michael Scott RA Root, David E. RA Benes, Cyril Henri RA Deshpande, Vikram RA Juric, Dejan RA Sellers, William Raj RA Ferrone, Cristina Rosa RA Haas, Wilhelm RA Vazquez, Francisca RA Getz, Gad RA Bardeesy, Nabeel M. RT "Generation of a biliary tract cancer cell line atlas reveals RT molecular subtypes and therapeutic targets."; RL bioRxiv 2024:07.04.601970-07.04.601970(2024). // RX PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416; RA Ku, Ja-Lok RA Park, Jae-Gahb RT "Biology of SNU cell lines."; RL Cancer Res. Treat. 37:1-19(2005). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX CelloPub=CLPUB00275; RA Zach, Sebastian RA Birgin, Emrullah RA Ruckert, Felix RT "Primary cholangiocellular carcinoma cell lines."; RL J. Stem Cell Res. Transplant. 2:1013-1013(2015). //