ID   DT40-MRE11(-/-)-XRCC6(-/-)
AC   CVCL_4Z66
SY   Delta-Mre11-delta-Ku70-DT40; DT40 MRE11-/-/KU70-/-
DR   CLO; CLO_0051530
DR   RCB; RCB1633
DR   Wikidata; Q54831497
RX   PubMed=10581236;
CC   Group: Bird cell line.
CC   Knockout cell: Method=Targeted integration; CGNC; 12932; MRE11.
CC   Knockout cell: Method=Targeted integration; CGNC; 9044; XRCC6.
CC   Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: Hy-Line SC.
DI   NCIt; C134556; Chicken bursal lymphoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
HI   CVCL_0249 ! DT40
SX   Female
AG   1D
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 10-09-24; Version: 12
//
RX   PubMed=10581236; DOI=10.1093/emboj/18.23.6619; PMCID=PMC1171725;
RA   Yamaguchi-Iwai, Yuko
RA   Sonoda, Eiichiro
RA   Sasaki, Masao S.
RA   Morrison, Ciaran
RA   Haraguchi, Tokuko
RA   Hiraoka, Yasushi
RA   Yamashita, Yukiko M.
RA   Yagi, Takashi
RA   Takata, Minoru
RA   Price, Carolyn
RA   Kakazu, Naoki
RA   Takeda, Shunichi
RT   "Mre11 is essential for the maintenance of chromosomal DNA in
RT   vertebrate cells.";
RL   EMBO J. 18:6619-6629(1999).
//