ID   DT40-MRE11(-/-)-XRCC6(-/-)
AC   CVCL_4Z66
SY   Delta-Mre11-delta-Ku70-DT40; DT40 MRE11-/-/KU70-/-
DR   CLO; CLO_0051530
DR   RCB; RCB1633
DR   Wikidata; Q54831497
RX   PubMed=10581236;
CC   Group: Bird cell line.
CC   Knockout cell: Method=Targeted integration; UniProtKB; Q9IAM7; MRE11.
CC   Knockout cell: Method=Targeted integration; UniProtKB; O93257; XRCC6.
CC   Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: Hy-Line SC.
DI   NCIt; C134556; Chicken bursal lymphoma
OX   NCBI_TaxID=9031; ! Gallus gallus (Chicken)
HI   CVCL_0249 ! DT40
SX   Female
AG   1D
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 30-01-24; Version: 11
//
RX   PubMed=10581236; DOI=10.1093/emboj/18.23.6619;
RA   Yamaguchi-Iwai Y., Sonoda E., Sasaki M.S., Morrison C., Haraguchi T.,
RA   Hiraoka Y., Yamashita Y.M., Yagi T., Takata M., Price C., Kakazu N.,
RA   Takeda S.;
RT   "Mre11 is essential for the maintenance of chromosomal DNA in
RT   vertebrate cells.";
RL   EMBO J. 18:6619-6629(1999).
//