ID   COLO206F-AR
AC   CVCL_4V92
DR   Wikidata; Q54814216
RX   PubMed=21098728;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:90227; Selumetinib (AZD6244).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1988 ! COLO 206F
SX   Male
AG   70Y
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 29-06-23; Version: 6
//
RX   PubMed=21098728; DOI=10.1126/scisignal.2001148;
RA   Corcoran R.B., Dias-Santagata D., Bergethon K., Iafrate A.J.,
RA   Settleman J., Engelman J.A.;
RT   "BRAF gene amplification can promote acquired resistance to MEK
RT   inhibitors in cancer cells harboring the BRAF V600E mutation.";
RL   Sci. Signal. 3:Ra84.1-Ra84.10(2010).
//