ID   HT29/L-OHP
AC   CVCL_4V74
DR   cancercelllines; CVCL_4V74
DR   Wikidata; Q54896596
RX   PubMed=26400331;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_31941; Oxaliplatin (Elotaxin; L-OHP).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0320 ! HT-29
SX   Female
AG   44Y
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 19-12-24; Version: 18
//
RX   PubMed=26400331; DOI=10.4238/2015.September.21.14;
RA   Xiang, Zheng
RA   Kang, Qing-Jie
RA   Xiang, X.
RT   "Gene and protein expression in the oxaliplatin-resistant HT29/L-OHP
RT   human colon cancer cell line.";
RL   Genet. Mol. Res. 14:11013-11022(2015).
//