ID   CFSC-2G
AC   CVCL_4U34
DR   Wikidata; Q54811454
RX   PubMed=7635427;
RX   PubMed=8394478;
RX   PubMed=17760834;
RX   PubMed=20594261;
RX   PubMed=36139474;
CC   Karyotypic information: Hyperdiploid karyotype (PubMed=36139474).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatic stellate cell; CL=CL_0000632.
CC   Breed/subspecies: Wistar; RS=RS_0000955.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_M104 ! CFSC
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 22-09-15; Last updated: 10-04-25; Version: 8
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RX   PubMed=7635427; DOI=10.1002/hep.1840220230;
RA   Inagaki Y., Truter S., Greenwel P., Rojkind M., Unoura M.,
RA   Kobayashi K., Ramirez F.;
RT   "Regulation of the alpha 2(I) collagen gene transcription in
RT   fat-storing cells derived from a cirrhotic liver.";
RL   Hepatology 22:573-579(1995).
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RX   PubMed=8394478;
RA   Greenwel P., Rubin J., Schwartz M., Hertzberg E.L., Rojkind M.;
RT   "Liver fat-storing cell clones obtained from a CCl4-cirrhotic rat are
RT   heterogeneous with regard to proliferation, expression of
RT   extracellular matrix components, interleukin-6, and connexin 43.";
RL   Lab. Invest. 69:210-216(1993).
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RX   PubMed=17760834; DOI=10.1111/j.1582-4934.2007.00060.x; PMCID=PMC3823251;
RA   Herrmann J., Gressner A.M., Weiskirchen R.;
RT   "Immortal hepatic stellate cell lines: useful tools to study hepatic
RT   stellate cell biology and function?";
RL   J. Cell. Mol. Med. 11:704-722(2007).
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RX   PubMed=20594261; DOI=10.1111/j.1440-1746.2009.06175.x;
RA   Gonzalez-Puertos V.Y., Hernandez-Perez E., Nuno-Lambarri N.,
RA   Ventura-Gallegos J.L., Lopez-Diazguerrero N.E., Robles-Diaz G.,
RA   Gutierrez-Ruiz M.C., Konigsberg M.;
RT   "Bcl-2 overexpression in hepatic stellate cell line CFSC-2G, induces a
RT   pro-fibrotic state.";
RL   J. Gastroenterol. Hepatol. 25:1306-1314(2010).
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RX   PubMed=36139474; DOI=10.3390/cells11182900; PMCID=PMC9497204;
RA   Nanda I., Schroder S.K., Steinlein C., Haaf T., Buhl E.M., Grimm D.G.,
RA   Weiskirchen R.;
RT   "Rat hepatic stellate cell line CFSC-2G: genetic markers and short
RT   tandem repeat profile useful for cell line authentication.";
RL   Cells 11:2900.1-2900.19(2022).
//