ID   AC16 [Human hybrid cardiomyocyte]
AC   CVCL_4U18
DR   ATCC; CRL-3568
DR   CLS; 305215
DR   Millipore; SCC109
DR   Wikidata; Q54607923
RX   Patent=US7223599;
RX   PubMed=15913645;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-1500.
CC   Characteristics: Hybrid of adult ventricular cardiomiocytes with a SV40 transformed, uridine auxotroph human fibroblast cell line devoid of mitochondrial DNA (PubMed=15913645).
CC   Characteristics: Can differentiate when cultured in mitogen-free medium. The cells may be used to study developmental regulation of cardiomyocytes (Millipore=SCC109).
CC   Doubling time: 24.49 hours (PubMed=15913645).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Heart, ventricle; UBERON=UBERON_0002082.
CC   Cell type: Cardiomyocyte; CL=CL_0002495.
ST   Source(s): Millipore=SCC109
ST   Amelogenin: X
ST   CSF1PO: 9,11,12
ST   D13S317: 12,13
ST   D16S539: 11,13
ST   D18S51: 12,17
ST   D21S11: 32.2,33.2
ST   D3S1358: 17,18
ST   D5S818: 9,11
ST   D7S820: 10,11,12
ST   D8S1179: 12,14
ST   FGA: 21,25
ST   Penta D: 2.2,9
ST   Penta E: 7,8,16
ST   TH01: 7,8,9.3
ST   TPOX: 11
ST   vWA: 16,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4U14 ! DWFb1-rho0
CA   Hybrid cell line
DT   Created: 22-09-15; Last updated: 02-05-24; Version: 9
//
RX   Patent=US7223599;
RA   Davidson M.M.;
RT   "Immortalization of human post-mitotic cells.";
RL   Patent number US7223599, 29-May-2007.
//
RX   PubMed=15913645; DOI=10.1016/j.yjmcc.2005.03.003;
RA   Davidson M.M., Nesti C., Palenzuela L., Walker W.F., Hernandez E.,
RA   Protas L., Hirano M., Isaac N.D.;
RT   "Novel cell lines derived from adult human ventricular
RT   cardiomyocytes.";
RL   J. Mol. Cell. Cardiol. 39:133-147(2005).
//