ID   C-378
AC   CVCL_4J79
SY   C378
DR   ATCC; CRL-2083
DR   cancercelllines; CVCL_4J79
DR   Wikidata; Q54799741
CC   Problematic cell line: Probably contaminated. The STR profile is identical to that of the RD-ES cell line. Originally thought to originate from a giant cell tumor excised in 1986 from tumor tissue of a 33 year old female patient.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 2 fusion (Ex7/Ex5) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (from parent cell line).
CC   Discontinued: ATCC; CRL-2083; true.
CC   Derived from site: In situ; Bone, humerus; UBERON=UBERON_0000976.
ST   Source(s): ATCC=CRL-2083
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 11
ST   D5S818: 11
ST   D7S820: 10
ST   TH01: 7
ST   TPOX: 9,11
ST   vWA: 17
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2169 ! RD-ES
SX   Male
AG   19Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 19-12-24; Version: 18
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