ID   CUTLL1
AC   CVCL_4966
SY   CUTLL-1; Columbia University T-cell Lymphoblastic Lymphoma 1
DR   ABM; T8008
DR   cancercelllines; CVCL_4966
DR   ChEMBL-Cells; CHEMBL4651374
DR   Cosmic; 1224376
DR   Cosmic; 1641388
DR   Millipore; SCC286
DR   PubChem_Cell_line; CVCL_4966
DR   Wikidata; Q54814867
RX   PubMed=16688224;
CC   Sequence variation: Gene fusion; HGNC; 7881; NOTCH1 + HGNC; 12155; TRB; Name(s)=TRB-NOTCH1, TCRB-NOTCH1 (PubMed=16688224).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (PubMed=16688224).
CC   Omics: Transcriptome analysis by microarray.
CC   Misspelling: CUTTL-1; Note=Occasionally.
CC   Misspelling: CUTTL1; Cosmic=1224376.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): Millipore
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11,13
ST   D13S317: 8,10,11,12
ST   D16S539: 9,10,11
ST   D18S51: 13,14,16,20,21
ST   D21S11: 29,31.2,32.2,33.2,34.2
ST   D3S1358: 14,15,17
ST   D5S818: 9,10,12
ST   D7S820: 8,10
ST   D8S1179: 11,12,13
ST   FGA: 19,21,22,24
ST   Penta D: 10,11,12,12.4,14
ST   Penta E: 8,10,12
ST   TH01: 6,7,9.3
ST   TPOX: 8,10
ST   vWA: 16,18,19
DI   NCIt; C7210; Childhood T lymphoblastic lymphoma
DI   ORDO; Orphanet_171918; T-cell non-Hodgkin lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 18
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RX   PubMed=16688224; DOI=10.1038/sj.leu.2404258;
RA   Palomero T., Barnes K.C., Real P.J., Glade Bender J.L., Sulis M.L.,
RA   Murty V.V.V.S., Colovai A.I., Balbin M., Ferrando A.A.;
RT   "CUTLL1, a novel human T-cell lymphoma cell line with t(7;9)
RT   rearrangement, aberrant NOTCH1 activation and high sensitivity to
RT   gamma-secretase inhibitors.";
RL   Leukemia 20:1279-1287(2006).
//