ID   LNCaP-CL1-GFP
AC   CVCL_4924
SY   CL1-GFP
DR   cancercelllines; CVCL_4924
DR   Wikidata; Q54902833
RX   PubMed=10992426;
CC   Population: Caucasian.
CC   Characteristics: Androgen-independent. Has highly locally invasive and metastatic properties.
CC   Sequence variation: Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: UniProtKB; P42212; GFP.
CC   Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3872 ! LNCaP-CL1
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
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RX   PubMed=10992426; DOI=10.1016/S0022-5347(05)67210-2;
RA   Patel B.J., Pantuck A.J., Zisman A., Tsui K.-H., Paik S.H.,
RA   Caliliw R., Sheriff S., Wu L., deKernion J.B., Tso C.-L.,
RA   Belldegrun A.S.;
RT   "CL1-GFP: an androgen independent metastatic tumor model for prostate
RT   cancer.";
RL   J. Urol. 164:1420-1425(2000).
//