ID   SSP-25
AC   CVCL_4902
SY   SSP25
DR   CLO; CLO_0050849
DR   BioSample; SAMN03472126
DR   Cell_Model_Passport; SIDM00275
DR   Cosmic; 1187339
DR   Cosmic; 1571786
DR   Cosmic; 2629287
DR   DepMap; ACH-001858
DR   RCB; RCB1293
DR   Wikidata; Q54955717
RX   CelloPub=CLPUB00275;
RX   PubMed=9358283;
RX   PubMed=15767549;
RX   PubMed=27231123;
RX   PubMed=31077409;
RX   PubMed=35640676;
RX   PubMed=39026794;
WW   Info; RCB; -; https://cell.brc.riken.jp/en/rcb/rbessp-25_announce
CC   Problematic cell line: Contaminated. Shown to be a ETK-1 derivative (RCB=RCB1293). Originally thought to originate from a 64 year old female patient with an intrahepatic cholangiocarcinoma.
CC   Part of: Biliary tract cancer cell line atlas.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: JFCR45 cancer cell line panel.
CC   Population: Japanese.
CC   Doubling time: 64 hours (PubMed=9358283).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
ST   Source(s): DepMap=ACH-001858; RCB=RCB1293
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 10,12
ST   D18S51: 21
ST   D21S11: 29
ST   D3S1358: 15
ST   D5S818: 10
ST   D7S820: 11
ST   D8S1179: 10,12
ST   FGA: 19,25
ST   Penta D: 14
ST   Penta E: 15
ST   TH01: 7,9.3
ST   TPOX: 8
ST   vWA: 14,17
DI   NCIt; C35417; Intrahepatic cholangiocarcinoma
DI   ORDO; Orphanet_70567; Cholangiocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1206 ! ETK-1
SX   Female
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 30
//
RX   PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737;
RA   Saha, Supriya Kumar
RA   Gordan, John D.
RA   Kleinstiver, Benjamin P.
RA   Vu, Phuong
RA   Najem, Mortada S.
RA   Yeo, Jia-Chi
RA   Shi, Lei
RA   Kato, Yasutaka
RA   Levin, Rebecca S.
RA   Webber, James T.
RA   Damon, Leah J.
RA   Egan, Regina K.
RA   Greninger, Patricia
RA   McDermott, Ultan
RA   Garnett, Mathew J.
RA   Jenkins, Roger L.
RA   Rieger-Christ, Kimberly M.
RA   Sullivan, Travis B.
RA   Hezel, Aram Francis
RA   Liss, Andrew S.
RA   Mizukami, Yusuke
RA   Goyal, Lipika
RA   Ferrone, Cristina Rosa
RA   Zhu, Andrew Xiu-Xuan
RA   Joung, Jae Keith
RA   Shokat, Kevan Michael
RA   Benes, Cyril Henri
RA   Bardeesy, Nabeel M.
RT   "Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity
RT   and SRC dependence in intrahepatic cholangiocarcinoma.";
RL   Cancer Discov. 6:727-739(2016).
//
RX   PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155;
RA   Isidan, Abdulkadir
RA   Yenigun, Ali
RA   Soma, Daiki
RA   Aksu, Eric
RA   Lopez, Kevin
RA   Park, Yujin
RA   Cross-Najafi, Arthur
RA   Li, Ping
RA   Kundu, Debjyoti
RA   House, Michael G.
RA   Chakraborty, Sanjukta
RA   Glaser, Shannon
RA   Kennedy, Lindsey
RA   Francis, Heather
RA   Zhang, Wen-Jun
RA   Alpini, Gianfranco D.
RA   Ekser, Burcin
RT   "Development and characterization of human primary cholangiocarcinoma
RT   cell lines.";
RL   Am. J. Pathol. 192:1200-1217(2022).
//
RX   PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448;
RA   Vijay, Vindhya
RA   Karisani, Negin
RA   Shi, Lei
RA   Hung, Yu-Han
RA   Vu, Phuong
RA   Kattel, Prabhat
RA   Kenney, Lauren
RA   Merritt, Joshua
RA   Adil, Ramzi
RA   Wu, Qi-Biao
RA   Zhen, Yuan-Li
RA   Morris, Robert
RA   Kreuzer, Johannes
RA   Kathiresan, Meena
RA   Herrera Lopez, Xcanda Ixchel
RA   Ellis, Haley
RA   Gritti, Ilaria G.
RA   Lecorgne, Lilian
RA   Farag, Ines
RA   Popa, Alexandra
RA   Shen, William
RA   Kato, Hiroyuki
RA   Xu, Qin
RA   Balasooriya, Eranga Roshan
RA   Wu, Meng-Ju
RA   Chaturantabut, Saireudee
RA   Kelley, Robin Kate
RA   Cleary, James Mark
RA   Lawrence, Michael Scott
RA   Root, David E.
RA   Benes, Cyril Henri
RA   Deshpande, Vikram
RA   Juric, Dejan
RA   Sellers, William Raj
RA   Ferrone, Cristina Rosa
RA   Haas, Wilhelm
RA   Vazquez, Francisca
RA   Getz, Gad
RA   Bardeesy, Nabeel M.
RT   "Generation of a biliary tract cancer cell line atlas reveals
RT   molecular subtypes and therapeutic targets.";
RL   bioRxiv 2024:07.04.601970-07.04.601970(2024).
//
RX   PubMed=9358283; DOI=10.1007/s11626-997-0125-z;
RA   Enjoji, Munechika
RA   Sakai, Hironori
RA   Nawata, Hajime
RA   Kajiyama, Kiyoshi
RA   Tsuneyoshi, Masazumi
RT   "Sarcomatous and adenocarcinoma cell lines from the same nodule of
RT   cholangiocarcinoma.";
RL   In Vitro Cell. Dev. Biol. Anim. 33:681-683(1997).
//
RX   PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234;
RA   Nakatsu, Noriyuki
RA   Yoshida, Yoko
RA   Yamazaki, Kanami
RA   Nakamura, Tomoki
RA   Dan, Shingo
RA   Fukui, Yasuhisa
RA   Yamori, Takao
RT   "Chemosensitivity profile of cancer cell lines and identification of
RT   genes determining chemosensitivity by an integrated bioinformatical
RT   approach using cDNA arrays.";
RL   Mol. Cancer Ther. 4:399-412(2005).
//
RX   PubMed=31077409; DOI=10.1002/hep.30704;
RA   Sittithumcharee, Gunya
RA   Suppramote, Orawan
RA   Vaeteewoottacharn, Kulthida
RA   Sirisuksakun, Chumphon
RA   Jamnongsong, Supawan
RA   Laphanuwat, Phatthamon
RA   Suntiparpluacha, Monthira
RA   Matha, Arriya
RA   Chusorn, Porncheera
RA   Buraphat, Pongsakorn
RA   Kakanaporn, Chumpot
RA   Charngkaew, Komgrid
RA   Silsirivanit, Atit
RA   Korphaisarn, Krittiya
RA   Limsrichamrern, Somchai
RA   Tripatara, Pinpat
RA   Pairojkul, Chawalit
RA   Wongkham, Sopit
RA   Sampattavanich, Somponnat
RA   Okada, Seiji
RA   Jirawatnotai, Siwanon
RT   "Dependency of cholangiocarcinoma on cyclin D-dependent kinase
RT   activity.";
RL   Hepatology 70:1614-1630(2019).
//
RX   CelloPub=CLPUB00275;
RA   Zach, Sebastian
RA   Birgin, Emrullah
RA   Ruckert, Felix
RT   "Primary cholangiocellular carcinoma cell lines.";
RL   J. Stem Cell Res. Transplant. 2:1013-1013(2015).
//