ID   PSK-1
AC   CVCL_4894
SY   PSK-I; Prostatic Small-cell carcinoma derived from a Klinefelter syndrome patient-1
DR   cancercelllines; CVCL_4894
DR   IARC_TP53; 18893
DR   Wikidata; Q54948568
RX   CelloPub=CLPUB00698;
RX   PubMed=10679758;
RX   PubMed=14518029;
RX   PubMed=14518030;
CC   Population: Japanese.
CC   Doubling time: ~34 hours (Note=At 15th passage), ~28 hours (Note=At 35th passage) (PubMed=10679758).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly279Glu (c.836G>A); ClinVar=VCV000419454; Zygosity=Unspecified (PubMed=14518029).
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
ST   Source(s): PubMed=14518029
ST   Amelogenin: X,Y
ST   D13S317: 11
ST   D18S51: 17
ST   D21S11: 30
ST   D3S1358: 15,17
ST   D5S818: 10,13
ST   D7S820: 10,11
ST   D8S1179: 13,14
ST   FGA: 23
ST   vWA: 14,18
DI   NCIt; C34752; Klinefelter syndrome
DI   NCIt; C6766; Prostate small cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   29Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
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RX   CelloPub=CLPUB00698;
RA   van Bokhoven A.;
RT   "Models for prostate cancer. Molecular characterization and critical
RT   appraisal of human prostate carcinoma cell lines.";
RL   Thesis PhD (2004); Katholieke Universiteit Nijmegen; Nijmegen; Netherlands.
//
RX   PubMed=10679758; DOI=10.1002/(SICI)1097-0045(20000301)42:4<287::AID-PROS6>3.0.CO;2-F;
RA   Kim C.J., Kushima R., Okada Y., Seto A.;
RT   "Establishment and characterization of a prostatic small-cell
RT   carcinoma cell line (PSK-1) derived from a patient with Klinefelter
RT   syndrome.";
RL   Prostate 42:287-294(2000).
//
RX   PubMed=14518029; DOI=10.1002/pros.10290;
RA   van Bokhoven A., Varella-Garcia M., Korch C.T., Johannes W.U.,
RA   Smith E.E., Miller H.L., Nordeen S.K., Miller G.J., Lucia M.S.;
RT   "Molecular characterization of human prostate carcinoma cell lines.";
RL   Prostate 57:205-225(2003).
//
RX   PubMed=14518030; DOI=10.1002/pros.10291;
RA   van Bokhoven A., Caires A., Di Maria M., Schulte A.P., Lucia M.S.,
RA   Nordeen S.K., Miller G.J., Varella-Garcia M.;
RT   "Spectral karyotype (SKY) analysis of human prostate carcinoma cell
RT   lines.";
RL   Prostate 57:226-244(2003).
//