ID   MDA-PCa-2a
AC   CVCL_4747
SY   MDA PCa 2a; MDAPC2A; MDA2A; M.D. Anderson-Prostate Cancer-2a
DR   ATCC; CRL-2421
DR   BioSample; SAMN03471839
DR   cancercelllines; CVCL_4747
DR   Cell_Model_Passport; SIDM01666
DR   GEO; GSM91925
DR   Progenetix; CVCL_4747
DR   Wikidata; Q54904652
RX   CelloPub=CLPUB00698;
RX   PubMed=9815652;
RX   PubMed=12725112;
RX   PubMed=14518029;
RX   PubMed=14518030;
RX   PubMed=15486987;
CC   Population: African American.
CC   Doubling time: 82 hours (Note=In BRFF-HPC1 + 20% FBS), 87-93 hours (Note=In F12K(+) + 20% FBS) (PubMed=9815652).
CC   Omics: Array-based CGH.
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: ATCC; CRL-2421; true.
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
ST   Source(s): ATCC=CRL-2421; PubMed=14518029
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 11,12
ST   D16S539: 10,11
ST   D18S51: 16,17
ST   D21S11: 31,32,33.2
ST   D3S1358: 14,17,18
ST   D5S818: 12,13
ST   D7S820: 8,10
ST   D8S1179: 14,15
ST   FGA: 19,22
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 15,16
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_4748 ! MDA-PCa-2b
SX   Male
AG   63Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 26
RX   CelloPub=CLPUB00698;
RA   van Bokhoven A.;
RT   "Models for prostate cancer. Molecular characterization and critical
RT   appraisal of human prostate carcinoma cell lines.";
RL   Thesis PhD (2004), Katholieke Universiteit Nijmegen, Netherlands.
RX   PubMed=9815652;
RA   Navone N.M., Olive M., Ozen M., Davis R., Troncoso P., Tu S.-M.,
RA   Johnston D., Pollack A., Pathak S., von Eschenbach A.C.,
RA   Logothetis C.J.;
RT   "Establishment of two human prostate cancer cell lines derived from a
RT   single bone metastasis.";
RL   Clin. Cancer Res. 3:2493-2500(1997).
RX   PubMed=12725112; DOI=10.1385/1-59259-372-0:21;
RA   Russell P.J., Kingsley E.A.;
RT   "Human prostate cancer cell lines.";
RL   Methods Mol. Med. 81:21-39(2003).
RX   PubMed=14518029; DOI=10.1002/pros.10290;
RA   van Bokhoven A., Varella-Garcia M., Korch C.T., Johannes W.U.,
RA   Smith E.E., Miller H.L., Nordeen S.K., Miller G.J., Lucia M.S.;
RT   "Molecular characterization of human prostate carcinoma cell lines.";
RL   Prostate 57:205-225(2003).
RX   PubMed=14518030; DOI=10.1002/pros.10291;
RA   van Bokhoven A., Caires A., Di Maria M., Schulte A.P., Lucia M.S.,
RA   Nordeen S.K., Miller G.J., Varella-Garcia M.;
RT   "Spectral karyotype (SKY) analysis of human prostate carcinoma cell
RT   lines.";
RL   Prostate 57:226-244(2003).
RX   PubMed=15486987; DOI=10.1002/pros.20158;
RA   Zhao H.-J., Kim Y., Wang P., Lapointe J., Tibshirani R., Pollack J.R.,
RA   Brooks J.D.;
RT   "Genome-wide characterization of gene expression variations and DNA
RT   copy number changes in prostate cancer cell lines.";
RL   Prostate 63:187-197(2005).