ID   DC3F/ADX
AC   CVCL_4705
SY   DC3F/Adx; DC3F-ADX; DC-3F/ADX; DC-3F/AD X
DR   BTO; BTO_0002395
DR   Wikidata; Q54828628
RX   PubMed=2158805;
RX   PubMed=3365701;
RX   PubMed=5533992;
RX   PubMed=7907088;
RX   PubMed=11455011;
CC   Selected for resistance to: ChEBI; CHEBI_27666; Actinomycin D (ActD).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_GZ08 ! DC3F/ADIV
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 12
//
RX   PubMed=2158805; DOI=10.1038/bjc.1990.127; PMCID=PMC1971365;
RA   Boscoboinik D.O., Gupta R.S., Epand R.M.;
RT   "Investigation of the relationship between altered intracellular pH
RT   and multidrug resistance in mammalian cells.";
RL   Br. J. Cancer 61:568-572(1990).
//
RX   PubMed=3365701;
RA   Biedler J.L., Chang T.-D., Scotto K.W., Melera P.W., Spengler B.A.;
RT   "Chromosomal organization of amplified genes in multidrug-resistant
RT   Chinese hamster cells.";
RL   Cancer Res. 48:3179-3187(1988).
//
RX   PubMed=5533992;
RA   Biedler J.L., Riehm H.;
RT   "Cellular resistance to actinomycin D in Chinese hamster cells in
RT   vitro: cross-resistance, radioautographic, and cytogenetic studies.";
RL   Cancer Res. 30:1174-1184(1970).
//
RX   PubMed=7907088; DOI=10.1016/S0021-9258(17)37579-8;
RA   Devine S.E., Melera P.W.;
RT   "Diversity of multidrug resistance in mammalian cells.";
RL   J. Biol. Chem. 269:6133-6139(1994).
//
RX   PubMed=11455011; DOI=10.1124/mol.60.2.254;
RA   Song J., Melera P.W.;
RT   "Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein
RT   that affects drug resistance and cooperates with TM6 to mediate
RT   [125I]iodoarylazidoprazosin labeling.";
RL   Mol. Pharmacol. 60:254-261(2001).
//