ID   5A-HS-MYC
AC   CVCL_4586
SY   5A HS MYC
DR   CLO; CLO_0002845
DR   ATCC; CRL-9010
DR   Wikidata; Q54604013
RX   Patent=EP0232845A2;
RX   PubMed=3526329;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9010.
CC   Characteristics: Expression of mouse Myc is under the control of a Drosophila hsp70 promoter. Contains ~2700 copies of the Myc gene (PubMed=3526329).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:97250; Myc.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Caution: ATCC CRL-9010 use DUKX B1 as the name of the cell line which is a misspelling of the parent cell line from Patent=EP0232845A2.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
//
RX   Patent=EP0232845A2;
RA   Kingston R.E., Wurm F.M.;
RT   "Inducible heat shock and amplification system.";
RL   Patent number EP0232845A2, 19-Aug-1987.
//
RX   PubMed=3526329; DOI=10.1073/pnas.83.15.5414; PMCID=PMC386297;
RA   Wurm F.M., Gwinn-Hardy K.A., Kingston R.E.;
RT   "Inducible overproduction of the mouse c-myc protein in mammalian
RT   cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 83:5414-5418(1986).
//