ID   CHO-DXB11 6E6
AC   CVCL_4582
SY   6E6
DR   CLO; CLO_0001459
DR   ATCC; CRL-11398
DR   Wikidata; Q54604541
RX   Patent=US5854070;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11398.
CC   Characteristics: Transfected with Ig heavy and light chains of humanized version of mAB produced by hybridoma 23F2g (Cellosaurus=CVCL_4W87).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
//
RX   Patent=US5854070;
RA   Rose L.M.;
RT   "Murine and humanized 23F2G antibodies and cell lines expressing said
RT   antibodies.";
RL   Patent number US5854070, 29-Dec-1998.
//