ID   SK-N-LO
AC   CVCL_4569
SY   SK-N-L0; SKN-LO; SKNLO
DR   BTO; BTO_0004787
DR   cancercelllines; CVCL_4569
DR   CLS; 300400
DR   Cosmic; 1078368
DR   Cosmic; 1212539
DR   GEO; GSM393039
DR   IGRhCellID; SKNLO%20GEO
DR   Progenetix; CVCL_4569
DR   Wikidata; Q54954476
RX   DOI=10.1159/000407025;
RX   PubMed=2987426;
RX   PubMed=6610792;
RX   PubMed=7591257;
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Sequence variation: Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1 (PubMed=7591257).
CC   Caution: It is not certain if this is a neuroblastoma cell line as indicated by CLS or an Ewing sarcoma cell line as indicated in PubMed=7591257.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): CLS=300400; COG
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,11
ST   D16S539: 12
ST   D18S51: 12
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 16,20
ST   D3S1358: 14,17
ST   D5S818: 11,12
ST   D7S820: 11
ST   D8S1179: 12,15
ST   FGA: 20,25 (COG)
ST   FGA: 25 (CLS=300400)
ST   Penta D: 9,13
ST   Penta E: 7
ST   TH01: 10
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   10Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 24
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RX   DOI=10.1159/000407025;
RA   Helson L., Verma M., Helson C.;
RT   "Vitamin E and human neuroblastoma.";
RL   (In book chapter) Modulation and mediation of cancer by vitamins; Meyskens F.L., Prasad K.N. (eds.); pp.258-265; Karger; Basel; Switzerland (1983).
//
RX   PubMed=2987426; DOI=10.1007/BF00165170;
RA   Helson L., Helson C.;
RT   "Human neuroblastoma cells and 13-cis-retinoic acid.";
RL   J. Neurooncol. 3:39-41(1985).
//
RX   PubMed=6610792; DOI=10.1093/jnci/73.1.51;
RA   Sugimoto T., Tatsumi E., Kemshead J.T., Helson L., Green A.A.,
RA   Minowada J.;
RT   "Determination of cell surface membrane antigens common to both human
RT   neuroblastoma and leukemia-lymphoma cell lines by a panel of 38
RT   monoclonal antibodies.";
RL   J. Natl. Cancer Inst. 73:51-57(1984).
//
RX   PubMed=7591257; DOI=10.1002/ijc.2910630407;
RA   Ida K., Kobayashi S., Taki T., Hanada R., Bessho F., Yamamori S.,
RA   Sugimoto T., Ohki M., Hayashi Y.;
RT   "EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive
RT   neuroectodermal tumor.";
RL   Int. J. Cancer 63:500-504(1995).
//