ID   IB3-1/C38
AC   CVCL_4462
SY   C38
DR   BTO; BTO_0004447
DR   CLO; CLO_0002118
DR   ATCC; CRL-2779
DR   ATCC; JHU-54
DR   BioSample; SAMN03471787
DR   Wikidata; Q54897164
RX   PubMed=1380129;
RX   PubMed=7679117;
RX   PubMed=18441018;
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1884; CFTR.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Discontinued: ATCC; CRL-2779; true.
CC   Discontinued: ATCC; JHU-54; true.
ST   Source(s): ATCC=CRL-2779
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 8,12,13
ST   D16S539: 9,11
ST   D5S818: 11,12,13
ST   D7S820: 11,12
ST   TH01: 8,9.3
ST   TPOX: 8,9
ST   vWA: 15,18
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0338 ! IB3-1
SX   Male
AG   7Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 15
//
RX   PubMed=7679117; DOI=10.1016/S0021-9258(18)53762-5;
RA   Flotte, Terence R.
RA   Afione, Sandra A.
RA   Solow, Rikki
RA   Drumm, Mitchell L.
RA   Markakis, Diane
RA   Guggino, William B.
RA   Zeitlin, Pamela L.
RA   Carter, Barrie J.
RT   "Expression of the cystic fibrosis transmembrane conductance regulator
RT   from a novel adeno-associated virus promoter.";
RL   J. Biol. Chem. 268:3781-3790(1993).
//
RX   PubMed=1380129; DOI=10.1038/358581a0;
RA   Egan, Marie
RA   Flotte, Terence R.
RA   Afione, Sandra A.
RA   Solow, Rikki
RA   Zeitlin, Pamela L.
RA   Carter, Barrie J.
RA   Guggino, William B.
RT   "Defective regulation of outwardly rectifying Cl- channels by protein
RT   kinase A corrected by insertion of CFTR.";
RL   Nature 358:581-584(1992).
//
RX   PubMed=18441018; DOI=10.1194/jlr.M700388-JLR200; PMCID=PMC2444007;
RA   Andersson, Charlotte
RA   Al-Turkmani, M. Rabie
RA   Savaille, Juanito E.
RA   Alturkmani, Ragheed
RA   Katrangi, Waddah
RA   Cluette-Brown, Joanne E.
RA   Zaman, Munir M.
RA   Laposata, Michael
RA   Freedman, Steven D.
RT   "Cell culture models demonstrate that CFTR dysfunction leads to
RT   defective fatty acid composition and metabolism.";
RL   J. Lipid Res. 49:1692-1700(2008).
//