ID   SU-DHL-7
AC   CVCL_4380
SY   SUDHL7; SUDHL-7; SuDHL 7; Stanford University-Diffuse Histiocytic Lymphoma-7; DHL-7; DHL7
DR   cancercelllines; CVCL_4380
DR   Cosmic; 850206
DR   Cosmic; 1290018
DR   Cosmic; 1517608
DR   Cosmic; 1541912
DR   Cosmic; 1945193
DR   Cosmic; 2276341
DR   Cosmic; 2361373
DR   DSMZ; ACC-903
DR   DSMZCellDive; ACC-903
DR   GEO; GSM380148
DR   GEO; GSM552466
DR   GEO; GSM1035335
DR   Progenetix; CVCL_4380
DR   Wikidata; Q54970722
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=83902;
RX   PubMed=214220;
RX   PubMed=371794;
RX   PubMed=3881165;
RX   PubMed=8547074;
RX   PubMed=9787181;
RX   PubMed=19278952;
RX   PubMed=19358282;
RX   PubMed=20628145;
RX   PubMed=23292937;
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00557.
CC   Doubling time: ~50 hours (DSMZ=ACC-903).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Caution: Was reported in Cellosaurus and the ICLAC Register (from 2018 to early 2022) to be a SU-DHL-8 contaminated cell line but there seem to have been an issue with the sample tested. DSMZ has obtained original stock from Epstein A.L. and SU-DHL-7 is a genuine non-problematic cell line.
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): DSMZ=ACC-903
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12,13
ST   D16S539: 9,12
ST   D18S51: 14,15
ST   D19S433: 12,14
ST   D21S11: 32.2
ST   D2S1338: 16,20
ST   D3S1358: 16
ST   D5S818: 11,13
ST   D7S820: 10,11
ST   D8S1179: 12,14
ST   FGA: 20,25
ST   Penta D: 13
ST   Penta E: 12,15
ST   TH01: 7,9.3
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C8851; Diffuse large B-cell lymphoma
DI   ORDO; Orphanet_544; Diffuse large B-cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 32
//
RX   PubMed=371794;
RA   Epstein, Alan L.
RA   Kaplan, Henry Seymour
RT   "Feeder layer and nutritional requirements for the establishment and
RT   cloning of human malignant lymphoma cell lines.";
RL   Cancer Res. 39:1748-1759(1979).
//
RX   PubMed=23292937; DOI=10.1073/pnas.1205299110; PMCID=PMC3557051;
RA   Zhang, Jenny
RA   Grubor, Vladimir
RA   Love, Cassandra L.
RA   Banerjee, Anjishnu
RA   Richards, Kristy L.
RA   Mieczkowski, Piotr Andrzej
RA   Dunphy, Cherie
RA   Choi, William Wai-Lap
RA   Au, Wing Yan
RA   Srivastava, Gopesh
RA   Lugar, Patricia Lynne
RA   Rizzieri, David A.
RA   Lagoo, Anand S.
RA   Bernal-Mizrachi, Leon
RA   Mann, Karen P.
RA   Flowers, Christopher Robert
RA   Naresh, Kikkeri N.
RA   Evens, Andrew M.
RA   Gordon, Leo I.
RA   Czader, Magdalena B.
RA   Gill, Javed Iqbal
RA   Hsi, Eric Darryl
RA   Liu, Qing-Quan
RA   Fan, Alice
RA   Walsh, Katherine
RA   Jima, Dereje
RA   Smith, Lisa L.
RA   Johnson, Amy J.
RA   Byrd, John C.
RA   Luftig, Micah Alan
RA   Ni, Ting
RA   Zhu, Jun
RA   Chadburn, Amy
RA   Levy, Shawn
RA   Dunson, David Brian
RA   Dave, Sandeep S.
RT   "Genetic heterogeneity of diffuse large B-cell lymphoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:1398-1403(2013).
//
RX   PubMed=19358282; DOI=10.1002/ijc.24351;
RA   Inagaki, Atsushi
RA   Ishida, Takashi
RA   Yano, Hiroki
RA   Ishii, Toshihiko
RA   Kusumoto, Shigeru
RA   Ito, Asahi
RA   Ri, Masaki
RA   Mori, Fumiko
RA   Ding, Jian-Min
RA   Komatsu, Hirokazu
RA   Iida, Shinsuke
RA   Ueda, Ryuzo
RT   "Expression of the ULBP ligands for NKG2D by B-NHL cells plays an
RT   important role in determining their susceptibility to
RT   rituximab-induced ADCC.";
RL   Int. J. Cancer 125:212-221(2009).
//
RX   PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x;
RA   Siebert, Reiner
RA   Willers, Christoph P.
RA   Schramm, Alexander
RA   Fossa, Alexander
RA   Dresen, Irina M. Gana
RA   Uppenkamp, Michael J.
RA   Nowrousian, Mohammad Resa
RA   Seeber, Siegfried
RA   Opalka, Bertram
RT   "Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and
RT   lymphoblastic leukaemia cell lines.";
RL   Br. J. Haematol. 91:350-354(1995).
//
RX   PubMed=3881165; DOI=10.1016/0165-4608(85)90186-4;
RA   Kaiser-McCaw Hecht, Barbara
RA   Epstein, Alan L.
RA   Berger, Carol S.
RA   Kaplan, Henry Seymour
RA   Hecht, Frederick
RT   "Histiocytic lymphoma cell lines: immunologic and cytogenetic
RT   studies.";
RL   Cancer Genet. Cytogenet. 14:205-218(1985).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=83902; DOI=10.1002/1097-0142(197901)43:1<1::AID-CNCR2820430102>3.0.CO;2-M;
RA   Kaplan, Henry Seymour
RA   Goodenow, Robert S.
RA   Gartner, Suzanne
RA   Bieber, Marcia M.
RT   "Biology and virology of the human malignant lymphomas: 1st Milford D.
RT   Schulz lecture.";
RL   Cancer 43:1-24(1979).
//
RX   PubMed=214220; DOI=10.1002/1097-0142(197811)42:5<2379::AID-CNCR2820420539>3.0.CO;2-4;
RA   Epstein, Alan L.
RA   Levy, Ronald
RA   Kim, Hun
RA   Henle, Werner
RA   Henle, Gertrude Szpingier
RA   Kaplan, Henry Seymour
RT   "Biology of the human malignant lymphomas. IV. Functional
RT   characterization of ten diffuse histiocytic lymphoma cell lines.";
RL   Cancer 42:2379-2391(1978).
//
RX   PubMed=19278952; DOI=10.1182/blood-2009-01-202028; PMCID=PMC3401058;
RA   Li, Cheng
RA   Kim, Sang-Woo
RA   Rai, Deepak
RA   Bolla, Aswani R.
RA   Adhvaryu, Siddharth
RA   Kinney, Marsha C.
RA   Robetorye, Ryan S.
RA   Aguiar, Ricardo C.T.
RT   "Copy number abnormalities, MYC activity, and the genetic fingerprint
RT   of normal B cells mechanistically define the microRNA profile of
RT   diffuse large B-cell lymphoma.";
RL   Blood 113:6681-6690(2009).
//
RX   PubMed=9787181; DOI=10.1182/blood.V92.9.3410;
RA   Sakai, Akira
RA   Thieblemont, Catherine
RA   Wellmann, Axel
RA   Jaffe, Elaine Sarkin
RA   Raffeld, Mark
RT   "PTEN gene alterations in lymphoid neoplasms.";
RL   Blood 92:3410-3415(1998).
//
RX   PubMed=20628145; DOI=10.1182/blood-2010-05-282780; PMCID=PMC2995356;
RA   Green, Michael Richard
RA   Monti, Stefano
RA   Rodig, Scott J.
RA   Juszczynski, Przemyslaw
RA   Currie, Treeve
RA   O'Donnell, Evan
RA   Chapuy, Bjoern
RA   Takeyama, Kunihiko
RA   Neuberg, Donna
RA   Golub, Todd Robert
RA   Kutok, Jeffery L.
RA   Shipp, Margaret Ann
RT   "Integrative analysis reveals selective 9p24.1 amplification,
RT   increased PD-1 ligand expression, and further induction via JAK2 in
RT   nodular sclerosing Hodgkin lymphoma and primary mediastinal large
RT   B-cell lymphoma.";
RL   Blood 116:3268-3277(2010).
//