ID   CHO-xrs-6
AC   CVCL_4340
SY   CHO-XrS6; CHO-XRS6; CHO XrS6; xrs-6; xrs 6; XrS6; XRS6; xrs6
DR   BTO; BTO:0004066
DR   CLO; CLO_0009692
DR   CLDB; cl4784
DR   ChEMBL-Cells; CHEMBL3307295
DR   ChEMBL-Targets; CHEMBL614060
DR   ECACC; 92052128
DR   PubChem_Cell_line; CVCL_4340
DR   Wikidata; Q54813132
RX   PubMed=2564870;
RX   PubMed=3785270;
RX   PubMed=6197643;
RX   PubMed=8799130;
RX   PubMed=9032253;
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 13
//
RX   PubMed=2564870; DOI=10.1080/09553008914550651;
RA   Denekamp J., Whitmore G.F., Jeggo P.A.;
RT   "Biphasic survival curves for XRS radiosensitive cells: subpopulations
RT   or transient expression of repair competence?";
RL   Int. J. Radiat. Biol. 55:605-617(1989).
//
RX   PubMed=3785270; DOI=10.1016/0167-8817(86)90025-8;
RA   Kemp L.M., Jeggo P.A.;
RT   "Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs)
RT   of the Chinese hamster ovary cell line.";
RL   Mutat. Res. 166:255-263(1986).
//
RX   PubMed=6197643; DOI=10.1016/0167-8817(83)90026-3;
RA   Jeggo P.A., Kemp L.M.;
RT   "X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation
RT   and cross-sensitivity to other DNA-damaging agents.";
RL   Mutat. Res. 112:313-327(1983).
//
RX   PubMed=8799130; DOI=10.1073/pnas.93.17.8929;
RA   Liang F., Romanienko P.J., Weaver D.T., Jeggo P.A., Jasin M.;
RT   "Chromosomal double-strand break repair in Ku80-deficient cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:8929-8933(1996).
//
RX   PubMed=9032253; DOI=10.1128/mcb.17.3.1264;
RA   Singleton B.K., Priestley A., Steingrimsdottir H., Gell D., Blunt T.,
RA   Jackson S.P., Lehmann A.R., Jeggo P.A.;
RT   "Molecular and biochemical characterization of xrs mutants defective
RT   in Ku80.";
RL   Mol. Cell. Biol. 17:1264-1273(1997).
//