ID   T7 [Mouse lung]
AC   CVCL_4314
DR   ECACC; 07021402
DR   Wikidata; Q54971597
RX   PubMed=10949996;
CC   Characteristics: Proliferates at permissive temperature (33-35 Celsius) in the presence of IFNG, terminally differentiates at restrictive temperature (39 Celsius) in the absence of IFNG.
CC   Doubling time: 48 hours (ECACC=07021402).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299.
CC   Cell type: Type 2 pneumocyte; CL=CL_0002063.
CC   Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Conditionally immortalized cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 13
//
RX   PubMed=10949996; DOI=10.1290/1071-2690(2000)036<0374:GOAIDL>2.0.CO;2; PMCID=PMC7101677;
RA   deMello, Daphne E.
RA   Mahmoud, Sohir
RA   Padfield, Philip J.
RA   Hoffmann, Joseph W.
RT   "Generation of an immortal differentiated lung type-II epithelial cell
RT   line from the adult H-2K(b)tsA58 transgenic mouse.";
RL   In Vitro Cell. Dev. Biol. Anim. 36:374-382(2000).
//