ID   PancTu-II
AC   CVCL_4013
SY   PancTuII; Panc-TU-II; Panc-Tu2; Panc Tu-II; PaTu II; PaTuII; PaTu-II; Pa Tu-II; Patu-2; PATU2; PaCa-2
DR   cancercelllines; CVCL_4013
DR   Cosmic; 736276
DR   Cosmic; 808162
DR   Cosmic; 933531
DR   Cosmic; 2664045
DR   IARC_TP53; 1562
DR   Wikidata; Q54937567
RX   PubMed=1998727;
RX   PubMed=2161859;
RX   PubMed=8194712;
RX   PubMed=8286197;
RX   PubMed=8426738;
RX   PubMed=11169959;
WW   https://www.cellosaurus.org/pawefish/PancCellLineDescriptions/PaTu%20II.html
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=8426738; PubMed=11169959).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Cys176Ser (c.526T>A); ClinVar=VCV000376570; Zygosity=Unspecified (PubMed=8426738; PubMed=11169959).
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_4012 ! PancTu-I
SX   Female
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 18
//
RX   PubMed=1998727; DOI=10.1016/0167-4838(91)90278-8;
RA   Flocke K., Mannherz H.G.;
RT   "Isolation and characterization of 5'-nucleotidase of a human
RT   pancreatic tumor cell line.";
RL   Biochim. Biophys. Acta 1076:273-281(1991).
//
RX   PubMed=2161859; DOI=10.1242/jcs.95.1.65;
RA   Mai M., Brune K., Jacoby B., Kern H.F., Mollenhauer J.A.;
RT   "Laminin interactions with ductal pancreatic adenocarcinoma cells:
RT   identification of laminin- and collagen-binding proteins.";
RL   J. Cell Sci. 95:65-74(1990).
//
RX   PubMed=8194712; DOI=10.1016/0016-5085(94)90422-7;
RA   Simon B., Weinel R., Hohne M., Watz J., Schmidt J., Kortner G.,
RA   Arnold R.;
RT   "Frequent alterations of the tumor suppressor genes p53 and DCC in
RT   human pancreatic carcinoma.";
RL   Gastroenterology 106:1645-1651(1994).
//
RX   PubMed=8286197; DOI=10.1038/bjc.1994.24;
RA   Lohr J.-M., Trautmann B., Gottler M., Peters S., Zauner I., Maillet B.,
RA   Kloppel G.;
RT   "Human ductal adenocarcinomas of the pancreas express extracellular
RT   matrix proteins.";
RL   Br. J. Cancer 69:144-151(1994).
//
RX   PubMed=8426738;
RA   Kalthoff H., Schmiegel W.H., Roeder C., Kasche D., Schmidt A., Lauer G.,
RA   Thiele H.-G., Honold G., Pantel K., Riethmuller G., Scherer E.,
RA   Maurer J., Maacke H., Deppert W.;
RT   "p53 and K-RAS alterations in pancreatic epithelial cell lesions.";
RL   Oncogene 8:289-298(1993).
//
RX   PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C;
RA   Sirivatanauksorn V., Sirivatanauksorn Y., Gorman P.A., Davidson J.M.,
RA   Sheer D., Moore P.S., Scarpa A., Edwards P.A.W., Lemoine N.R.;
RT   "Non-random chromosomal rearrangements in pancreatic cancer cell lines
RT   identified by spectral karyotyping.";
RL   Int. J. Cancer 91:350-358(2001).
//