ID   PancTu-I
AC   CVCL_4012
SY   PancTu-1; PancTu 1; Panc-TU-I; Panc-Tu1; Panc-TuI; Panc Tu-I; Panc TUI; PancTuI; PancTUI; PaTu-I; PaTu I; PatuI; PaTu1
DR   EFO; EFO_0002715
DR   cancercelllines; CVCL_4012
DR   Cosmic; 710865
DR   Cosmic; 736275
DR   Cosmic; 933530
DR   Cosmic; 1534321
DR   GEO; GSM244424
DR   Progenetix; CVCL_4012
DR   Wikidata; Q54937559
RX   DOI=10.22029/jlupub-12385;
RX   PubMed=8426738;
RX   PubMed=11169959;
RX   PubMed=11787853;
RX   PubMed=12692724;
RX   PubMed=12800145;
RX   PubMed=18298655;
RX   PubMed=19077451;
WW   Info; Pawefish; -; https://www.cellosaurus.org/pawefish/PancCellLineDescriptions/PaTu%201.html
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (PubMed=8426738; PubMed=11169959; PubMed=11787853).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Ser (c.526T>A); ClinVar=VCV000376570; Zygosity=Unspecified (PubMed=8426738; PubMed=11169959; PubMed=11787853).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_4013 ! PancTu-II
SX   Female
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 22
//
RX   PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C;
RA   Sirivatanauksorn, Vorapan
RA   Sirivatanauksorn, Yongyut
RA   Gorman, Patricia A.
RA   Davidson, Jeffrey M.
RA   Sheer, Denise
RA   Moore, Patrick S.
RA   Scarpa, Aldo
RA   Edwards, Paul A.W.
RA   Lemoine, Nicholas Robert
RT   "Non-random chromosomal rearrangements in pancreatic cancer cell lines
RT   identified by spectral karyotyping.";
RL   Int. J. Cancer 91:350-358(2001).
//
RX   PubMed=12800145; DOI=10.1002/gcc.10218;
RA   Adelaide, Jose
RA   Huang, Huai-En
RA   Murati, Anne
RA   Alsop, Amber E.
RA   Orsetti, Beatrice
RA   Mozziconacci, Marie-Joelle
RA   Popovici, Cornel
RA   Ginestier, Christophe
RA   Letessier, Anne
RA   Basset, Celine
RA   Courtay-Cahen, Celine
RA   Jacquemier, Jocelyne
RA   Theillet, Charles
RA   Birnbaum, Daniel
RA   Edwards, Paul A.W.
RA   Chaffanet, Max
RT   "A recurrent chromosome translocation breakpoint in breast and
RT   pancreatic cancer cell lines targets the neuregulin/NRG1 gene.";
RL   Genes Chromosomes Cancer 37:333-345(2003).
//
RX   DOI=10.22029/jlupub-12385;
RA   Oberlin, Laura
RT   "Treatment of pancreatic carcinoma cell lines in vitro and vivo with a
RT   monoclonal antibody against the transferrin receptor.";
RL   Thesis VMD (2009); Justus-Liebig-Universitat Giessen; Giessen; Germany.
//
RX   PubMed=8426738;
RA   Kalthoff, Holger
RA   Schmiegel, Wolff Helmut
RA   Roeder, Christian
RA   Kasche, Daniela
RA   Schmidt, Andreas
RA   Lauer, Georg
RA   Thiele, Heinz-Gunter
RA   Honold, Georg
RA   Pantel, Klaus
RA   Riethmuller, Gert
RA   Scherer, Ewalt
RA   Maurer, Julian
RA   Maacke, Heiko
RA   Deppert, Wolfgang
RT   "p53 and K-RAS alterations in pancreatic epithelial cell lesions.";
RL   Oncogene 8:289-298(1993).
//
RX   PubMed=18298655; DOI=10.1111/j.1582-4934.2008.00289.x; PMCID=PMC3828895;
RA   Pilarsky, Christian
RA   Ammerpohl, Ole
RA   Sipos, Bence
RA   Dahl, Edgar
RA   Hartmann, Arndt
RA   Wellmann, Axel
RA   Braunschweig, Till
RA   Lohr, Johannes-Matthias
RA   Jesenofsky, Ralf
RA   Friess, Helmut
RA   Wente, Moritz Nicolas
RA   Kristiansen, Glen
RA   Jahnke, Beatrix
RA   Denz, Axel
RA   Ruckert, Felix
RA   Schackert, Hans Konrad
RA   Kloppel, Gunter
RA   Kalthoff, Holger
RA   Saeger, Hans-Detlev
RA   Grutzmann, Robert
RT   "Activation of Wnt signalling in stroma from pancreatic cancer
RT   identified by gene expression profiling.";
RL   J. Cell. Mol. Med. 12:2823-2835(2008).
//
RX   PubMed=19077451; DOI=10.1159/000178871;
RA   Harada, Tomohiko
RA   Chelala, Claude
RA   Crnogorac-Jurcevic, Tatjana
RA   Lemoine, Nicholas Robert
RT   "Genome-wide analysis of pancreatic cancer using microarray-based
RT   techniques.";
RL   Pancreatology 9:13-24(2009).
//
RX   PubMed=11787853; DOI=10.1007/s004280100474;
RA   Moore, Patrick S.
RA   Sipos, Bence
RA   Orlandini, Simonetta
RA   Sorio, Claudio
RA   Real, Francisco X.
RA   Lemoine, Nicholas Robert
RA   Gress, Thomas M.
RA   Bassi, Claudio
RA   Kloppel, Gunter
RA   Kalthoff, Holger
RA   Ungefroren, Hendrik
RA   Lohr, Johannes-Matthias
RA   Scarpa, Aldo
RT   "Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras,
RT   p53, p16 and DPC4/Smad4.";
RL   Virchows Arch. 439:798-802(2001).
//
RX   PubMed=12692724; DOI=10.1007/s00428-003-0784-4;
RA   Sipos, Bence
RA   Moser, Simone
RA   Kalthoff, Holger
RA   Torok, Virag
RA   Lohr, Johannes-Matthias
RA   Kloppel, Gunter
RT   "A comprehensive characterization of pancreatic ductal carcinoma cell
RT   lines: towards the establishment of an in vitro research platform.";
RL   Virchows Arch. 442:444-452(2003).
//