ID   HP
AC   CVCL_3715
SY   HT1080 poly
DR   CLO; CLO_0003797
DR   ATCC; CRL-12012
DR   cancercelllines; CVCL_3715
DR   Cell_Model_Passport; SIDM01214
DR   Wikidata; Q54890193
RX   Patent=US5591624;
CC   Group: Patented cell line.
CC   Group: Retrovirus packaging cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12012.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Discontinued: ATCC; CRL-12012; true.
CC   Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
ST   Source(s): ATCC=CRL-12012
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 12,14
ST   D16S539: 9,12
ST   D5S818: 11,13
ST   D7S820: 9,10
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 14,19
DI   NCIt; C3043; Fibrosarcoma
DI   ORDO; Orphanet_2030; Fibrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0317 ! HT-1080
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 24
//
RX   Patent=US5591624;
RA   Barber, Jack R.
RA   Jolly, Douglas J.
RA   Respess, James G.
RA   Chang, Stephen M.W.
RT   "Retroviral packaging cell lines.";
RL   Patent number US5591624, 07-Jan-1997.
//