ID   LNZTA3WT11
AC   CVCL_3539
SY   LNZTA3p53WT11; WT11
DR   CLO; CLO_0007370
DR   LINCS_LDP; LCL-1355
DR   Wikidata; Q54902865
RX   Patent=US5807731;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11544.
CC   Population: Caucasian.
CC   Characteristics: The expression of the luciferase reporter gene as well as the TP53 gene are under the control of a tetO operator.
CC   Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16.
CC   Transfected with: HGNC; 11998; TP53.
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Brain, right parieto-occipital lobe.
ST   Source(s): ATCC
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11
ST   D16S539: 9,12
ST   D5S818: 12
ST   D7S820: 10,12
ST   TH01: 9.3
ST   TPOX: 8,9
ST   vWA: 15,17
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0394 ! LN-308
SX   Male
AG   60Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 17
//
RX   Patent=US5807731;
RA   Van Meir E.G., Huang H.-J.S., Cavenee W.K.;
RT   "Glioblastoma cell lines that produce angiogenesis inhibiting
RT   factor.";
RL   Patent number US5807731, 15-Sep-1998.
//