ID   HCC3153
AC   CVCL_3377
SY   HCC 3153; HCC-3153; Hamon Cancer Center 3153
DR   CLO; CLO_0009910
DR   EFO; EFO_0001179
DR   ArrayExpress; E-TABM-157
DR   BioSample; SAMN03470870
DR   cancercelllines; CVCL_3377
DR   Cosmic; 1136375
DR   Cosmic; 1176634
DR   DepMap; ACH-002324
DR   GEO; GSM350507
DR   GEO; GSM1053691
DR   GEO; GSM1172874
DR   GEO; GSM1172966
DR   GEO; GSM3145576
DR   GEO; GSM3145709
DR   LINCS_HMS; 51094
DR   LINCS_LDP; LCL-2075
DR   PharmacoDB; HCC3153_498_2019
DR   Progenetix; CVCL_3377
DR   Wikidata; Q54881686
RX   PubMed=17157791;
RX   PubMed=19582160;
RX   PubMed=20679594;
RX   PubMed=21778573;
RX   PubMed=22032724;
RX   PubMed=24094812;
RX   PubMed=24176112;
RX   PubMed=25877200;
RX   PubMed=25960936;
WW   Info; Synapse; JWGray panel; https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
WW   Provider; UT Southwestern; -; https://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: JWGray breast cancer cell line panel.
CC   Doubling time: 72.26 hours (JWGray panel).
CC   HLA typing: A*34:02,34:02; B*08:01,15:03; C*07:01,02:02; DQB1*06:04,06:04 (PubMed=25960936).
CC   Sequence variation: Gene fusion; HGNC; HGNC:290; GRK3 + HGNC; HGNC:29435; WWC1; Name(s)=WWC1-GRK3, WWC1-ADRBK2; Note=In frame (PubMed=22032724).
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Thr276Alafs*14 (c.815_824dupAGCCATGTGG); ClinVar=VCV000055723; Zygosity=Unspecified (PubMed=22032724).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F.
ST   Source(s): Direct_author_submission; PubMed=20679594; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D10S1248: 12,14
ST   D12S391: 18
ST   D13S317: 9
ST   D16S539: 11
ST   D18S51: 17
ST   D19S433: 12,14.2
ST   D1S1656: 12
ST   D21S11: 28,32
ST   D22S1045: 11,17
ST   D2S1338: 20
ST   D2S441: 11
ST   D3S1358: 16
ST   D5S818: 11
ST   D7S820: 9,10
ST   D8S1179: 13
ST   FGA: 19
ST   Penta D: 2.2,5
ST   Penta E: 7,13
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 13,16
DI   NCIt; C4017; Breast ductal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 14-08-25; Version: 34
//
RX   PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590;
RA   Daemen, Anneleen
RA   Griffith, Obi L.
RA   Heiser, Laura M.
RA   Wang, Nicholas J.
RA   Enache, Oana M.
RA   Sanborn, Zachary
RA   Pepin, Francois
RA   Durinck, Steffen
RA   Korkola, James E.
RA   Griffith, Malachi
RA   Hur, Joe S.
RA   Huh, Nam
RA   Chung, Jongsuk
RA   Cope, Leslie
RA   Fackler, Mary Jo
RA   Umbricht, Christopher Benedict
RA   Sukumar, Saraswati
RA   Seth, Pankaj
RA   Sukhatme, Vikas P.
RA   Jakkula, Lakshmi R.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Cho, Raymond J.
RA   Collisson, Eric A.
RA   van 't Veer, Laura J.
RA   Spellman, Paul T.
RA   Gray, Joe W.
RT   "Modeling precision treatment of breast cancer.";
RL   Genome Biol. 14:R110.1-R110.14(2013).
//
RX   PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474;
RA   Gazdar, Adi F.
RA   Girard, Luc
RA   Lockwood, William W.
RA   Lam, Wan L.
RA   Minna, John D.
RT   "Lung cancer cell lines as tools for biomedical discovery and
RT   research.";
RL   J. Natl. Cancer Inst. 102:1310-1321(2010).
//
RX   PubMed=21778573; DOI=10.3233/BD-2010-0307; PMCID=PMC3532890;
RA   Chavez, Kathryn J.
RA   Garimella, Sireesha V.
RA   Lipkowitz, Stanley
RT   "Triple negative breast cancer cell lines: one tool in the search for
RT   better treatment of triple negative breast cancer.";
RL   Breast Dis. 32:35-48(2010).
//
RX   PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020; PMCID=PMC3931310;
RA   Timmerman, Luika A.
RA   Holton, Thomas
RA   Yuneva, Mariia
RA   Louie, Raymond J.
RA   Padro, Merce
RA   Daemen, Anneleen
RA   Hu, Min
RA   Chan, Denise A.
RA   Ethier, Stephen P.
RA   van 't Veer, Laura J.
RA   Polyak, Kornelia
RA   McCormick, Frank
RA   Gray, Joe W.
RT   "Glutamine sensitivity analysis identifies the xCT antiporter as a
RT   common triple-negative breast tumor therapeutic target.";
RL   Cancer Cell 24:450-465(2013).
//
RX   PubMed=22032724; DOI=10.1186/1755-8794-4-75; PMCID=PMC3227591;
RA   Ha, Kevin C.H.
RA   Lalonde, Emilie
RA   Li, Li-Li
RA   Cavallone, Luca
RA   Natrajan, Rachael
RA   Lambros, Maryou B.
RA   Mitsopoulos, Costas
RA   Hakas, Jarle
RA   Kozarewa, Iwanka
RA   Fenwick, Kerry
RA   Lord, Christopher J.
RA   Ashworth, Alan
RA   Vincent-Salomon, Anne
RA   Basik, Mark
RA   Reis-Filho, Jorge Sergio
RA   Majewski, Jacek
RA   Foulkes, William D.
RT   "Identification of gene fusion transcripts by transcriptome sequencing
RT   in BRCA1-mutated breast cancers and cell lines.";
RL   BMC Med. Genomics 4:75.1-75.13(2011).
//
RX   PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981;
RA   Boegel, Sebastian
RA   Lower, Martin
RA   Bukur, Thomas
RA   Sahin, Ugur
RA   Castle, John C.
RT   "A catalog of HLA type, HLA expression, and neo-epitope candidates in
RT   human cancer cell lines.";
RL   OncoImmunology 3:e954893.1-e954893.12(2014).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008; PMCID=PMC2730521;
RA   Neve, Richard M.
RA   Chin, Koei
RA   Fridlyand, Jane
RA   Yeh, Jennifer
RA   Baehner, Frederick L.
RA   Fevr, Tea
RA   Clark, Laura
RA   Bayani, Nora
RA   Coppe, Jean-Philippe
RA   Tong, Frances
RA   Speed, Terry
RA   Spellman, Paul T.
RA   DeVries, Sandy
RA   Lapuk, Anna
RA   Wang, Nick J.
RA   Kuo, Wen-Lin
RA   Stilwell, Jackie L.
RA   Pinkel, Daniel
RA   Albertson, Donna G.
RA   Waldman, Frederic M.
RA   McCormick, Frank
RA   Dickson, Robert Brent
RA   Johnson, Michael D.
RA   Lippman, Marc E.
RA   Ethier, Stephen P.
RA   Gazdar, Adi F.
RA   Gray, Joe W.
RT   "A collection of breast cancer cell lines for the study of
RT   functionally distinct cancer subtypes.";
RL   Cancer Cell 10:515-527(2006).
//
RX   PubMed=19582160; DOI=10.1371/journal.pone.0006146; PMCID=PMC2702084;
RA   Kao, Jessica
RA   Salari, Keyan
RA   Bocanegra, Melanie
RA   Choi, Yoon-La
RA   Girard, Luc
RA   Gandhi, Jeet
RA   Kwei, Kevin A.
RA   Hernandez-Boussard, Tina
RA   Wang, Pei
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Pollack, Jonathan R.
RT   "Molecular profiling of breast cancer cell lines defines relevant
RT   tumor models and provides a resource for cancer gene discovery.";
RL   PLoS ONE 4:e6146.1-e6146.16(2009).
//