ID   HCC1007
AC   CVCL_3374
SY   HCC-1007; Hamon Cancer Center 1007
DR   EFO; EFO_0001168
DR   ATCC; CRL-2318
DR   BioSample; SAMN03471869
DR   cancercelllines; CVCL_3374
DR   GEO; GSM350518
DR   IARC_TP53; 10270
DR   KCLB; 9S1007
DR   Progenetix; CVCL_3374
DR   Wikidata; Q54881517
RX   PubMed=9833771;
RX   PubMed=9865903;
RX   PubMed=11314036;
RX   PubMed=17157791;
RX   PubMed=19582160;
RX   PubMed=24094812;
WW   https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
CC   Part of: JWGray breast cancer cell line panel.
CC   Population: African American.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Asp281His (c.841G>C); ClinVar=VCV000376588; Zygosity=Unspecified (PubMed=9865903).
CC   Omics: CNV analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: ATCC; CRL-2318; true.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
ST   Source(s): ATCC=CRL-2318; KCLB=9S1007
ST   Amelogenin: X
ST   CSF1PO: 12,13
ST   D13S317: 12
ST   D16S539: 14,15
ST   D3S1358: 16
ST   D5S818: 13
ST   D7S820: 10
ST   FGA: 23
ST   TH01: 7
ST   TPOX: 6,11
ST   vWA: 16,19 (KCLB=9S1007)
ST   vWA: 19 (ATCC=CRL-2318)
DI   NCIt; C4017; Breast ductal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_3282 ! HCC1007 BL
OI   CVCL_1244 ! HCC1008
SX   Female
AG   67Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 28
//
RX   PubMed=9833771; DOI=10.1002/(SICI)1097-0215(19981209)78:6<766::AID-IJC15>3.0.CO;2-L;
RA   Gazdar A.F., Kurvari V., Virmani A.K., Gollahon L., Sakaguchi M.,
RA   Westerfield M., Kodagoda D.R., Stasny V., Cunningham H.T., Wistuba I.I.,
RA   Tomlinson G.E., Tonk V., Ashfaq R., Leitch A.M., Minna J.D., Shay J.W.;
RT   "Characterization of paired tumor and non-tumor cell lines established
RT   from patients with breast cancer.";
RL   Int. J. Cancer 78:766-774(1998).
//
RX   PubMed=9865903;
RA   Wistuba I.I., Behrens C., Milchgrub S., Syed S., Ahmadian M.,
RA   Virmani A.K., Kurvari V., Cunningham T.H., Ashfaq R., Minna J.D.,
RA   Gazdar A.F.;
RT   "Comparison of features of human breast cancer cell lines and their
RT   corresponding tumors.";
RL   Clin. Cancer Res. 4:2931-2938(1998).
//
RX   PubMed=11314036; DOI=10.1038/sj.onc.1204211;
RA   Forgacs E., Wren J.D., Kamibayashi C., Kondo M., Xu X.L.,
RA   Markowitz S.D., Tomlinson G.E., Muller C.Y., Gazdar A.F., Garner H.R.,
RA   Minna J.D.;
RT   "Searching for microsatellite mutations in coding regions in lung,
RT   breast, ovarian and colorectal cancers.";
RL   Oncogene 20:1005-1009(2001).
//
RX   PubMed=17157791; DOI=10.1016/j.ccr.2006.10.008;
RA   Neve R.M., Chin K., Fridlyand J., Yeh J., Baehner F.L., Fevr T.,
RA   Clark L., Bayani N., Coppe J.-P., Tong F., Speed T., Spellman P.T.,
RA   DeVries S., Lapuk A., Wang N.J., Kuo W.-L., Stilwell J.L., Pinkel D.,
RA   Albertson D.G., Waldman F.M., McCormick F., Dickson R.B.,
RA   Johnson M.D., Lippman M.E., Ethier S.P., Gazdar A.F., Gray J.W.;
RT   "A collection of breast cancer cell lines for the study of
RT   functionally distinct cancer subtypes.";
RL   Cancer Cell 10:515-527(2006).
//
RX   PubMed=19582160; DOI=10.1371/journal.pone.0006146;
RA   Kao J., Salari K., Bocanegra M., Choi Y.-L., Girard L., Gandhi J.,
RA   Kwei K.A., Hernandez-Boussard T., Wang P., Gazdar A.F., Minna J.D.,
RA   Pollack J.R.;
RT   "Molecular profiling of breast cancer cell lines defines relevant
RT   tumor models and provides a resource for cancer gene discovery.";
RL   PLoS ONE 4:E6146-E6146(2009).
//
RX   PubMed=24094812; DOI=10.1016/j.ccr.2013.08.020;
RA   Timmerman L.A., Holton T., Yuneva M., Louie R.J., Padro M., Daemen A.,
RA   Hu M., Chan D.A., Ethier S.P., van 't Veer L.J., Polyak K.,
RA   McCormick F., Gray J.W.;
RT   "Glutamine sensitivity analysis identifies the xCT antiporter as a
RT   common triple-negative breast tumor therapeutic target.";
RL   Cancer Cell 24:450-465(2013).
//