ID   ZFL
AC   CVCL_3276
SY   ZF-L; ZebraFish Liver; ZLE; Zebrafish Liver Epithelium
DR   CLO; CLO_0009725
DR   ATCC; CRL-2643
DR   BCRC; 60454
DR   BCRJ; 0256
DR   FCS-free; 154-27-282-1-4-3
DR   Wikidata; Q54995906
RX   DOI=10.1007/BF01404818;
RX   PubMed=7994634;
RX   PubMed=24355757;
RX   PubMed=25536407;
RX   PubMed=28587087;
CC   Group: Fish cell line.
CC   Doubling time: 2.54 +- 0.28 days (Note=In L-15-FBS), 6.6 +- 0.43 days (Note=In UltraMEM-ITES) (PubMed=28587087); 72 hours (ATCC=CRL-2643).
CC   Donor information: According to PubMed 7994634 obtained from pooling the livers of three fish, while ATCC mentions 10 individuals (ATCC=CRL-2643; PubMed=7994634).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
OX   NCBI_TaxID=7955; ! Danio rerio (Zebrafish)
SX   Sex unspecified
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 21
//
RX   DOI=10.1007/BF01404818;
RA   Bradford C.S., Sun L., Collodi P., Barnes D.W.;
RT   "Cell cultures from zebrafish embryos and adult tissues.";
RL   J. Tissue Cult. Methods 16:99-107(1994).
//
RX   PubMed=7994634; DOI=10.1007/BF00757560;
RA   Ghosh C., Zhou Y.L., Collodi P.;
RT   "Derivation and characterization of a zebrafish liver cell line.";
RL   Cell Biol. Toxicol. 10:167-176(1994).
//
RX   PubMed=24355757; DOI=10.1016/j.aquatox.2013.11.023;
RA   Eide M., Rusten M., Male R., Jensen K.H.M., Goksoyr A.;
RT   "A characterization of the ZFL cell line and primary hepatocytes as in
RT   vitro liver cell models for the zebrafish (Danio rerio).";
RL   Aquat. Toxicol. 147:7-17(2014).
//
RX   PubMed=25536407; DOI=10.1016/j.cbpb.2014.12.002;
RA   Ruyra A., Torrealba D., Morera D., Tort L., MacKenzie S., Roher N.;
RT   "Zebrafish liver (ZFL) cells are able to mount an anti-viral response
RT   after stimulation with poly (I:C).";
RL   Comp. Biochem. Physiol. 182B:55-63(2015).
//
RX   PubMed=28587087; DOI=10.3390/md15060147;
RA   Liu C.-L., Watson A.M., Place A.R., Jagus R.;
RT   "Taurine biosynthesis in a fish liver cell line (ZFL) adapted to a
RT   serum-free medium.";
RL   Mar. Drugs 15:147.1-147.15(2017).
//