ID   Lu-65A
AC   CVCL_3012
SY   LU-65A; LU65A
DR   CLO; CLO_0037025
DR   BioSample; SAMN03472811
DR   cancercelllines; CVCL_3012
DR   Cosmic; 753590
DR   Cosmic; 1001659
DR   GEO; GSM827386
DR   Progenetix; CVCL_3012
DR   Wikidata; Q54903207
RX   PubMed=9023415;
RX   PubMed=9290701;
RX   PubMed=20215515;
CC   Population: Japanese.
CC   HLA typing: A*11:01,24:02; B*40:02; C*03:04 (PubMed=9023415).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Ser82Ter (c.245C>A); ClinVar=VCV000837710; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu11Gln (c.31G>C); ClinVar=VCV000041723; Zygosity=Homozygous (from parent cell line).
CC   Omics: SNP array analysis.
CC   Misspelling: LC-95A; PubMed=9023415.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
ST   Source(s): JCRB=JCRB0054
ST   Amelogenin: X
ST   CSF1PO: 13
ST   D13S317: 10
ST   D16S539: 9,11
ST   D5S818: 12
ST   D7S820: 11,12
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 18
DI   NCIt; C4452; Lung giant cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1392 ! Lu-65
SX   Male
AG   64Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 27
RX   PubMed=9023415; DOI=10.1006/cimm.1996.1062;
RA   Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.;
RT   "HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating
RT   lymphocytes of patients with non-small cell lung cancer.";
RL   Cell. Immunol. 175:101-110(1997).
RX   PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D;
RA   Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T.,
RA   Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M.,
RA   Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.;
RT   "Screening the p53 status of human cell lines using a yeast functional
RT   assay.";
RL   Mol. Carcinog. 19:243-253(1997).
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).