ID   MCF-7/VD(R)
AC   CVCL_2Z97
DR   cancercelllines; CVCL_2Z97
DR   Wikidata; Q54904397
RX   PubMed=11500919;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_27300; Vitamin D.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 19-12-24; Version: 15
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RX   PubMed=11500919; DOI=10.1002/jcb.1162;
RA   Hansen, Christina Mork
RA   Rohde, Lili
RA   Madsen, Mogens W.
RA   Hansen, Dann
RA   Colston, Kay W.
RA   Pirianov, Grisha
RA   Holm, Pernille Kaae
RA   Binderup, Lise
RT   "MCF-7/VD(R): a new vitamin D resistant cell line.";
RL   J. Cell. Biochem. 82:422-436(2001).
//