ID   SRD-12A
AC   CVCL_2H50
SY   Sterol Regulatory Defective-12A
DR   Wikidata; Q54955655
RX   PubMed=9774448;
CC   Characteristics: Has a defect in the site 1 cleavage reaction.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:15455; MBTPS2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCIt; C129643; Cesium-137 gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_2H49 ! CHO/pS2P
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 22-09-15; Last updated: 14-08-25; Version: 11
//
RX   PubMed=9774448; DOI=10.1074/jbc.273.43.28261;
RA   Rawson, Robert B.
RA   Cheng, Dong
RA   Brown, Michael Stuart
RA   Goldstein, Joseph Leonard
RT   "Isolation of cholesterol-requiring mutant Chinese hamster ovary cells
RT   with defects in cleavage of sterol regulatory element-binding proteins
RT   at site 1.";
RL   J. Biol. Chem. 273:28261-28269(1998).
//