ID   AG13153
AC   CVCL_2F62
SY   AG_13153; GRC#1545
DR   CLO; CLO_0022104
DR   Coriell; AG13153
DR   GEO; GSM6361
DR   GEO; GSM6389
DR   GEO; GSM244117
DR   GEO; GSM244118
DR   GEO; GSM3124570
DR   Wikidata; Q54744757
RX   CelloPub=CLPUB00597;
RX   PubMed=9724752;
RX   PubMed=12840040;
RX   PubMed=16081512;
RX   PubMed=18368133;
RX   PubMed=18631391;
RX   PubMed=30567591;
CC   Part of: Baltimore Longitudinal Study of Aging (BLSA) cell line collection.
CC   Population: Caucasian.
CC   Senescence: Senesces at 33 PDL (PubMed=9724752).
CC   Doubling time: 2.3 days (PubMed=12840040).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_2B66 ! AG06234
SX   Male
AG   30Y
CA   Finite cell line
DT   Created: 22-09-15; Last updated: 29-06-23; Version: 15
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RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994).
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RX   PubMed=9724752; DOI=10.1073/pnas.95.18.10614;
RA   Cristofalo V.J., Allen R.G., Pignolo R.J., Martin B.G., Beck J.C.;
RT   "Relationship between donor age and the replicative lifespan of human
RT   cells in culture: a reevaluation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 95:10614-10619(1998).
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RX   PubMed=12840040; DOI=10.1101/gr.1289803;
RA   Karaman M.W., Houck M.L., Chemnick L.G., Nagpal S., Chawannakul D.,
RA   Sudano D., Pike B.L., Ho V.V., Ryder O.A., Hacia J.G.;
RT   "Comparative analysis of gene-expression patterns in human and African
RT   great ape cultured fibroblasts.";
RL   Genome Res. 13:1619-1630(2003).
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RX   PubMed=16081512; DOI=10.1093/carcin/bgi204;
RA   Khan S.G., Oh K.-S., Shahlavi T., Ueda T., Busch D.B., Inui H.,
RA   Emmert S., Imoto K., Muniz-Medina V., Baker C.C., DiGiovanna J.J.,
RA   Schmidt D., Khadavi A., Metin A., Gozukara E.M., Slor H., Sarasin A.,
RA   Kraemer K.H.;
RT   "Reduced XPC DNA repair gene mRNA levels in clinically normal parents
RT   of xeroderma pigmentosum patients.";
RL   Carcinogenesis 27:84-94(2006).
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RX   PubMed=18368133; DOI=10.1038/jid.2008.48;
RA   Inui H., Oh K.-S., Nadem C., Ueda T., Khan S.G., Metin A., Gozukara E.M.,
RA   Emmert S., Slor H., Busch D.B., Baker C.C., DiGiovanna J.J.,
RA   Tamura D., Seitz C.S., Gratchev A., Wu W.-H., Chung K.Y., Chung H.J.,
RA   Azizi E., Woodgate R., Schneider T.D., Kraemer K.H.;
RT   "Xeroderma pigmentosum-variant patients from America, Europe, and
RT   Asia.";
RL   J. Invest. Dermatol. 128:2055-2068(2008).
//
RX   PubMed=18631391; DOI=10.1186/1742-4933-5-5;
RA   Kriete A., Mayo K.L., Yalamanchili N., Beggs W., Bender P., Kari C.,
RA   Rodeck U.;
RT   "Cell autonomous expression of inflammatory genes in biologically aged
RT   fibroblasts associated with elevated NF-kappaB activity.";
RL   Immun. Ageing 5:5.1-5.8(2008).
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RX   PubMed=30567591; DOI=10.1186/s13059-018-1599-6;
RA   Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A.,
RA   Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.;
RT   "Predicting age from the transcriptome of human dermal fibroblasts.";
RL   Genome Biol. 19:221.1-221.8(2018).
//