ID KMS-27 AC CVCL_2993 SY KMS27; Kawasaki Medical School-27 DR EFO; EFO_0006616 DR ArrayExpress; E-MTAB-2706 DR ArrayExpress; E-MTAB-2770 DR BioSample; SAMN03472924 DR BioSample; SAMN10987819 DR cancercelllines; CVCL_2993 DR Cell_Model_Passport; SIDM01573 DR CGH-DB; 25-1 DR CGH-DB; 9138-4 DR Cosmic; 2391811 DR DepMap; ACH-000576 DR EGA; EGAS00001000610 DR GEO; GSM143347 DR GEO; GSM290299 DR GEO; GSM887226 DR GEO; GSM888300 DR IARC_TP53; 30104 DR JCRB; JCRB1188 DR JCRB; NIHS0488 DR LiGeA; CCLE_594 DR PharmacoDB; KMS27_769_2019 DR Progenetix; CVCL_2993 DR Wikidata; Q54900176 RX CelloPub=CLPUB00604; RX PubMed=15215163; RX PubMed=15491288; RX PubMed=17171682; RX PubMed=18700954; RX PubMed=19306352; RX PubMed=22460905; RX PubMed=25485619; RX PubMed=25877200; RX PubMed=26589293; RX PubMed=28196595; RX PubMed=30285677; RX PubMed=30894373; RX PubMed=31068700; RX PubMed=31978347; RX PubMed=32123307; WW Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines WW Info; MCLP; -; https://tcpaportal.org/mclp/ CC Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). CC Part of: MD Anderson Cell Lines Project. CC Population: Japanese. CC HLA typing: A*02:01,26:01; B*40:03,40:03; C*03:04,03:04 (PubMed=26589293). CC Omics: Genomics; Whole exome sequencing. CC Omics: Proteomics; Expression; Reverse-phase protein array. CC Omics: Proteomics; Quantitative. CC Omics: Transcriptomics; Microarray. CC Omics: Transcriptomics; RNAseq. CC Omics: Variations; Array-based CGH. CC Omics: Variations; SNP array analysis. CC Genome ancestry: African=0%; Native American=0.28%; East Asian, North=76.27%; East Asian, South=23.45%; South Asian=0%; European, North=0%; European, South=0% (PubMed=30894373). CC Discontinued: JCRB; NIHS0488; true. CC Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. CC Cell type: Plasma cell; CL=CL_0000786. ST Source(s): JCRB=JCRB1188; PubMed=25877200 ST Amelogenin: X,Y ST CSF1PO: 10,12 ST D13S317: 10,11 ST D16S539: 11,12 ST D18S51: 14,16 ST D21S11: 30,32.2 ST D3S1358: 16,17 ST D5S818: 10,12 ST D7S820: 11 ST D8S1179: 11,12 ST FGA: 22,23 ST Penta D: 9,12 ST Penta E: 13,18.4 ST TH01: 6,9 ST TPOX: 8 ST vWA: 14,17 DI NCIt; C3242; Plasma cell myeloma DI ORDO; Orphanet_29073; Multiple myeloma OX NCBI_TaxID=9606; ! Homo sapiens (Human) SX Male AG 52Y CA Cancer cell line DT Created: 04-04-12; Last updated: 14-08-25; Version: 32 // RX PubMed=25877200; DOI=10.1038/nature14397; RA Yu, Ma-Mie RA Selvaraj, Suresh K. RA Liang-Chu, May M.Y. RA Aghajani, Sahar RA Busse, Matthew RA Yuan, Jean RA Lee, Genee RA Peale, Franklin V. RA Klijn, Christiaan RA Bourgon, Richard RA Kaminker, Joshua S. RA Neve, Richard M. RT "A resource for cell line authentication, annotation and quality RT control."; RL Nature 520:307-311(2015). // RX CelloPub=CLPUB00604; RA Chow, Sharon RT "Targeted capture and sequencing of immunoglobulin rearrangements RT in multiple myeloma to enable detection of minimal residual disease."; RL Thesis MSc (2017); University of Toronto; Toronto; Canada. // RX PubMed=18700954; DOI=10.1186/1755-8794-1-37; PMCID=PMC2531129; RA Ronchetti, Domenica RA Lionetti, Marta RA Mosca, Laura RA Agnelli, Luca RA Andronache, Adrian RA Fabris, Sonia RA Lambertenghi-Deliliers, Giorgio RA Neri, Antonino RT "An integrative genomic approach reveals coordinated expression of RT intronic miR-335, miR-342, and miR-561 with deregulated host genes in RT multiple myeloma."; RL BMC Med. Genomics 1:37.1-37.9(2008). // RX PubMed=25485619; DOI=10.1038/nbt.3080; RA Klijn, Christiaan RA Durinck, Steffen RA Stawiski, Eric W. RA Haverty, Peter M. RA Jiang, Zhao-Shi RA Liu, Han-Bin RA Degenhardt, Jeremiah RA Mayba, Oleg RA Gnad, Florian RA Liu, Jin-Feng RA Pau, Gregoire RA Reeder, Jens RA Cao, Yi RA Mukhyala, Kiran RA Selvaraj, Suresh K. RA Yu, Ma-Mie RA Zynda, Gregory J. RA Brauer, Matthew J. RA Wu, Thomas D. RA Gentleman, Robert Clifford RA Manning, Gerard RA Yauch, Robert L. RA Bourgon, Richard RA Stokoe, David RA Modrusan, Zora RA Neve, Richard M. RA de Sauvage, Frederic J. RA Settleman, Jeffrey RA Seshagiri, Somasekar RA Zhang, Ze-Min RT "A comprehensive transcriptional portrait of human cancer cell RT lines."; RL Nat. Biotechnol. 33:306-312(2015). // RX PubMed=32123307; DOI=10.1038/s41375-020-0785-1; PMCID=PMC7483300; RA Sarin, Vishesh RA Yu, Katharine RA Ferguson, Ian D. RA Gugliemini, Olivia RA Nix, Matthew A. RA Hann, Byron RA Sirota, Marina RA Wiita, Arun P. RT "Evaluating the efficacy of multiple myeloma cell lines as models for RT patient tumors via transcriptomic correlation analysis."; RL Leukemia 34:2754-2765(2020). // RX PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103; RA Ghandi, Mahmoud RA Huang, Franklin W. RA Jane-Valbuena, Judit RA Kryukov, Gregory V. RA Lo, Christopher C. RA McDonald, E. Robert 3rd RA Barretina, Jordi Ginesta RA Gelfand, Ellen T. RA Bielski, Craig M. RA Li, Hao-Xin RA Hu, Kevin RA Andreev-Drakhlin, Alexander Y. RA Kim, Jaegil RA Hess, Julian M. RA Haas, Brian J. RA Aguet, Francois RA Weir, Barbara A. RA Rothberg, Michael V. RA Paolella, Brenton R. RA Lawrence, Michael Scott RA Akbani, Rehan RA Lu, Yi-Ling RA Tiv, Hong L. RA Gokhale, Prafulla C. RA de Weck, Antoine RA Mansour, Ali Amin RA Oh, Coyin RA Shih, Juliann RA Hadi, Kevin RA Rosen, Yanay RA Bistline, Jonathan RA Venkatesan, Kavitha RA Reddy, Anupama RA Sonkin, Dmitriy RA Liu, Manway RA Lehar, Joseph RA Korn, Joshua M. RA Porter, Dale A. RA Jones, Michael D. RA Golji, Javad RA Caponigro, Giordano RA Taylor, Jordan E. RA Dunning, Caitlin M. RA Creech, Amanda L. RA Warren, Allison C. RA McFarland, James M. RA Zamanighomi, Mahdi RA Kauffmann, Audrey RA Stransky, Nicolas RA Imielinski, Marcin RA Maruvka, Yosef E. RA Cherniack, Andrew D. RA Tsherniak, Aviad RA Vazquez, Francisca RA Jaffe, Jacob D. RA Lane, Andrew Alan RA Weinstock, David M. RA Johannessen, Cory M. RA Morrissey, Michael P. RA Stegmeier, Frank RA Schlegel, Robert RA Hahn, William Chun RA Getz, Gad RA Mills, Gordon B. RA Boehm, Jesse S. RA Golub, Todd Robert RA Garraway, Levi Alexander RA Sellers, William Raj RT "Next-generation characterization of the Cancer Cell Line RT Encyclopedia."; RL Nature 569:503-508(2019). // RX PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076; RA Li, Jun RA Zhao, Wei RA Akbani, Rehan RA Liu, Wen-Bin RA Ju, Zhen-Lin RA Ling, Shi-Yun RA Vellano, Christopher P. RA Roebuck, Paul RA Yu, Qing-Hua RA Eterovic, Agda Karina RA Byers, Lauren Averett RA Davies, Michael A. RA Deng, Wan-Leng RA Gopal, Y.N. Vashisht RA Chen, Guo RA von Euw, Erika Maria RA Slamon, Dennis Joseph RA Conklin, Dylan RA Heymach, John Victor RA Gazdar, Adi F. RA Minna, John D. RA Myers, Jeffrey N. RA Lu, Yi-Ling RA Mills, Gordon B. RA Liang, Han RT "Characterization of human cancer cell lines by reverse-phase protein RT arrays."; RL Cancer Cell 31:225-239(2017). // RX PubMed=17171682; DOI=10.1002/gcc.20404; RA Lombardi, Luigia RA Poretti, Giulia RA Mattioli, Michela RA Fabris, Sonia RA Agnelli, Luca RA Bicciato, Silvio RA Kwee, Ivo RA Rinaldi, Andrea RA Ronchetti, Domenica RA Verdelli, Donata RA Lambertenghi-Deliliers, Giorgio RA Bertoni, Francesco RA Neri, Antonino RT "Molecular characterization of human multiple myeloma cell lines by RT integrative genomics: insights into the biology of the disease."; RL Genes Chromosomes Cancer 46:226-238(2007). // RX PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027; RA Barretina, Jordi Ginesta RA Caponigro, Giordano RA Stransky, Nicolas RA Venkatesan, Kavitha RA Margolin, Adam A. RA Kim, Sungjoon RA Wilson, Christopher J. RA Lehar, Joseph RA Kryukov, Gregory V. RA Sonkin, Dmitriy RA Reddy, Anupama RA Liu, Manway RA Murray, Lauren RA Berger, Michael F. RA Monahan, John E. RA Morais, Paula RA Meltzer, Jodi RA Korejwa, Adam RA Jane-Valbuena, Judit RA Mapa, Felipa A. RA Thibault, Joseph RA Bric-Furlong, Eva RA Raman, Pichai RA Shipway, Aaron RA Engels, Ingo H. RA Cheng, Jill RA Yu, Guo-Ying K. RA Yu, Jian-Jun RA Aspesi, Peter Jr. RA de Silva, Melanie RA Jagtap, Kalpana RA Jones, Michael D. RA Wang, Li RA Hatton, Charles RA Palescandolo, Emanuele RA Gupta, Supriya RA Mahan, Scott RA Sougnez, Carrie RA Onofrio, Robert C. RA Liefeld, Ted RA MacConaill, Laura Eleanor RA Winckler, Wendy RA Reich, Michael RA Li, Nan-Xin RA Mesirov, Jill P. RA Gabriel, Stacey B. RA Getz, Gad RA Ardlie, Kristin RA Chan, Vivien RA Myer, Vic E. RA Weber, Barbara L. RA Porter, Jeff RA Warmuth, Markus RA Finan, Peter RA Harris, Jennifer L. RA Meyerson, Matthew Langer RA Golub, Todd Robert RA Morrissey, Michael P. RA Sellers, William Raj RA Schlegel, Robert RA Garraway, Levi Alexander RT "The Cancer Cell Line Encyclopedia enables predictive modelling of RT anticancer drug sensitivity."; RL Nature 483:603-607(2012). // RX PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878; RA Scholtalbers, Jelle RA Boegel, Sebastian RA Bukur, Thomas RA Byl, Marius RA Goerges, Sebastian RA Sorn, Patrick RA Loewer, Martin RA Sahin, Ugur RA Castle, John C. RT "TCLP: an online cancer cell line catalogue integrating HLA type, RT predicted neo-epitopes, virus and gene expression."; RL Genome Med. 7:118.1-118.7(2015). // RX PubMed=31978347; DOI=10.1016/j.cell.2019.12.023; PMCID=PMC7339254; RA Nusinow, David Paul RA Szpyt, John RA Ghandi, Mahmoud RA Rose, Christopher M. RA McDonald, E. Robert 3rd RA Kalocsay, Marian RA Jane-Valbuena, Judit RA Gelfand, Ellen T. RA Schweppe, Devin Karl RA Jedrychowski, Mark P. RA Golji, Javad RA Porter, Dale A. RA Rejtar, Tomas RA Wang, Y. Karen RA Kryukov, Gregory V. RA Stegmeier, Frank RA Erickson, Brian K. RA Garraway, Levi Alexander RA Sellers, William Raj RA Gygi, Steven P. RT "Quantitative proteomics of the Cancer Cell Line Encyclopedia."; RL Cell 180:387-402.e16(2020). // RX PubMed=15491288; DOI=10.1111/j.1365-2141.2004.05205.x; RA Otsuki, Takemi RA Yata, Kenichiro RA Takata-Tomokuni, Akiko RA Hyodoh, Fuminori RA Miura, Yoshie RA Sakaguchi, Haruko RA Hatayama, Tamayo RA Hatada, Seigo RA Tsujioka, Takayuki RA Sato, Yuko RA Murakami, H. RA Sadahira, Yoshito RA Sugihara, Takashi RT "Expression of protein gene product 9.5 (PGP9.5)/ubiquitin-C-terminal RT hydrolase 1 (UCHL-1) in human myeloma cells."; RL Br. J. Haematol. 127:292-298(2004). // RX PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675; RA Dutil, Julie RA Chen, Zhi-Hua RA Monteiro, Alvaro N.A. RA Teer, Jamie K. RA Eschrich, Steven A. RT "An interactive resource to probe genetic diversity and estimated RT ancestry in cancer cell lines."; RL Cancer Res. 79:1263-1273(2019). // RX PubMed=19306352; DOI=10.1002/gcc.20660; RA Lionetti, Marta RA Agnelli, Luca RA Mosca, Laura RA Fabris, Sonia RA Andronache, Adrian RA Todoerti, Katia RA Ronchetti, Domenica RA Lambertenghi-Deliliers, Giorgio RA Neri, Antonino RT "Integrative high-resolution microarray analysis of human myeloma cell RT lines reveals deregulated miRNA expression associated with allelic RT imbalances and gene expression profiles."; RL Genes Chromosomes Cancer 48:521-531(2009). // RX PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786; RA Tan, Kar-Tong RA Ding, Ling-Wen RA Sun, Qiao-Yang RA Lao, Zhen-Tang RA Chien, Wenwen RA Ren, Xi RA Xiao, Jin-Fen RA Loh, Xin-Yi RA Xu, Liang RA Lill, Michael RA Mayakonda, Anand RA Lin, De-Chen RA Yang, Henry He RA Koeffler, Harold Phillip RT "Profiling the B/T cell receptor repertoire of lymphocyte derived cell RT lines."; RL BMC Cancer 18:940.1-940.13(2018). // RX PubMed=15215163; DOI=10.1016/S0002-9440(10)63276-2; PMCID=PMC1618545; RA Inoue, Jun RA Otsuki, Takemi RA Hirasawa, Akira RA Imoto, Issei RA Matsuo, Yoshinobu RA Shimizu, Shiroh RA Taniwaki, Masafumi RA Inazawa, Johji RT "Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be RT associated with drug-resistance phenotype in multiple myeloma."; RL Am. J. Pathol. 165:71-81(2004). //