ID   UM-UC-7
AC   CVCL_2752
SY   UMUC7; University of Michigan-Urothelial Carcinoma-7
DR   cancercelllines; CVCL_2752
DR   Cell_Model_Passport; SIDM01402
DR   Cosmic; 1927296
DR   Cosmic; 1938704
DR   Cosmic; 2037970
DR   Cosmic; 2700985
DR   DepMap; ACH-001415
DR   ECACC; 08090504
DR   GEO; GSM1567865
DR   GEO; GSM1574564
DR   Wikidata; Q54990994
RX   PubMed=3761468;
RX   PubMed=18812553;
RX   PubMed=23401075;
RX   PubMed=24018021;
RX   PubMed=25997541;
RX   PubMed=29732388;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   Doubling time: 41 hours (PubMed=3761468).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (DepMap=ACH-001415).
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
ST   Source(s): DepMap=ACH-001415; ECACC=08090504
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 12 (ECACC=08090504)
ST   D13S317: 8,12 (DepMap=ACH-001415)
ST   D16S539: 10,11
ST   D18S51: 13
ST   D21S11: 31,32
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 14
ST   FGA: 20,22
ST   Penta D: 12,13
ST   Penta E: 7
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 16
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 26
//
RX   PubMed=3761468; DOI=10.1016/S0022-5347(17)45139-1;
RA   Grossman H.B., Wedemeyer G., Ren L.-Q., Wilson G.N., Cox B.;
RT   "Improved growth of human urothelial carcinoma cell cultures.";
RL   J. Urol. 136:953-959(1986).
//
RX   PubMed=18812553; DOI=10.1093/jnci/djn304;
RA   Park H.-S., Park W.S., Bondaruk J., Tanaka N., Katayama H., Lee S.,
RA   Spiess P.E., Steinberg J.R., Wang Z., Katz R.L., Dinney C.P.N.,
RA   Elias K.J., Lotan Y., Naeem R.C., Baggerly K., Sen S., Grossman H.B.,
RA   Czerniak B.;
RT   "Quantitation of Aurora kinase A gene copy number in urine sediments
RT   and bladder cancer detection.";
RL   J. Natl. Cancer Inst. 100:1401-1411(2008).
//
RX   PubMed=23401075; DOI=10.1002/path.4176;
RA   Guo Y.-N., Chekaluk Y., Zhang J.-M., Du J.-Y., Gray N.S., Wu C.-L.,
RA   Kwiatkowski D.J.;
RT   "TSC1 involvement in bladder cancer: diverse effects and therapeutic
RT   implications.";
RL   J. Pathol. 230:17-27(2013).
//
RX   PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052;
RA   Allory Y., Beukers W., Sagrera A., Flandez M., Marques M., Marquez M.,
RA   van der Keur K.A., Dyrskjot L., Lurkin I., Vermeij M., Carrato A.,
RA   Lloreta J., Lorente J.A., Carrillo-de-Santa-Pau E., Masius R.G.,
RA   Kogevinas M., Steyerberg E.W., van Tilborg A.A.G., Abas C.,
RA   Orntoft T.F., Zuiverloon T.C.M., Malats N., Zwarthoff E.C., Real F.X.;
RT   "Telomerase reverse transcriptase promoter mutations in bladder
RT   cancer: high frequency across stages, detection in urine, and lack of
RT   association with outcome.";
RL   Eur. Urol. 65:360-366(2014).
//
RX   PubMed=25997541; DOI=10.1186/s12864-015-1450-3;
RA   Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B.,
RA   Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G.,
RA   Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D.,
RA   Chanock S.J., Valencia A., Real F.X.;
RT   "The UBC-40 Urothelial Bladder Cancer cell line index: a genomic
RT   resource for functional studies.";
RL   BMC Genomics 16:403.1-403.16(2015).
//
RX   PubMed=29732388; DOI=10.3233/BLC-180167;
RA   Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.;
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//