ID   UM-UC-7
AC   CVCL_2752
SY   UMUC7; University of Michigan-Urothelial Carcinoma-7
DR   cancercelllines; CVCL_2752
DR   CancerTools; 160438
DR   Cell_Model_Passport; SIDM01402
DR   Cosmic; 1927296
DR   Cosmic; 1938704
DR   Cosmic; 2037970
DR   Cosmic; 2700985
DR   DepMap; ACH-001415
DR   ECACC; 08090504
DR   GEO; GSM1567865
DR   GEO; GSM1574564
DR   Wikidata; Q54990994
RX   PubMed=3761468;
RX   PubMed=18812553;
RX   PubMed=23401075;
RX   PubMed=24018021;
RX   PubMed=25997541;
RX   PubMed=29732388;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   Doubling time: 41 hours (PubMed=3761468).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (DepMap=ACH-001415).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Discontinued: ECACC; 08090504; true.
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
ST   Source(s): DepMap=ACH-001415; ECACC=08090504
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 8,12 (DepMap=ACH-001415)
ST   D13S317: 12 (ECACC=08090504)
ST   D16S539: 10,11
ST   D18S51: 13
ST   D21S11: 31,32
ST   D3S1358: 15
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 14
ST   FGA: 20,22
ST   Penta D: 12,13
ST   Penta E: 7
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 16
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 29
//
RX   PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052;
RA   Allory, Yves
RA   Beukers, Willemien
RA   Sagrera, Ana
RA   Flandez, Marta
RA   Marques, Miriam
RA   Marquez, Mirari
RA   van der Keur, Kirstin A.
RA   Dyrskjot, Lars
RA   Lurkin, Irene
RA   Vermeij, Marcel
RA   Carrato, Alfredo
RA   Lloreta, Josep
RA   Lorente, Jose A.
RA   Carrillo-de-Santa-Pau, Enrique
RA   Masius, Roy Geordi
RA   Kogevinas, Manolis
RA   Steyerberg, Ewout Willem
RA   van Tilborg, Angela A.G.
RA   Abas, Cheno
RA   Orntoft, Torben Falck
RA   Zuiverloon, Tahlita C.M.
RA   Malats, Nuria
RA   Zwarthoff, Ellen C.
RA   Real, Francisco X.
RT   "Telomerase reverse transcriptase promoter mutations in bladder
RT   cancer: high frequency across stages, detection in urine, and lack of
RT   association with outcome.";
RL   Eur. Urol. 65:360-366(2014).
//
RX   PubMed=23401075; DOI=10.1002/path.4176;
RA   Guo, Ya-Nan
RA   Chekaluk, Yvonne
RA   Zhang, Jian-Ming
RA   Du, Jin-Yan
RA   Gray, Nathanael S.
RA   Wu, Chin-Lee
RA   Kwiatkowski, David Joseph
RT   "TSC1 involvement in bladder cancer: diverse effects and therapeutic
RT   implications.";
RL   J. Pathol. 230:17-27(2013).
//
RX   PubMed=3761468; DOI=10.1016/S0022-5347(17)45139-1;
RA   Grossman, Herbert Barton
RA   Wedemeyer, Gary
RA   Ren, Li-Qin
RA   Wilson, Golder N.
RA   Cox, Beth
RT   "Improved growth of human urothelial carcinoma cell cultures.";
RL   J. Urol. 136:953-959(1986).
//
RX   PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350;
RA   Zuiverloon, Tahlita C.M.
RA   de Jong, Florus Christiaan
RA   Costello, James C.
RA   Theodorescu, Dan
RT   "Systematic review: characteristics and preclinical uses of bladder
RT   cancer cell lines.";
RL   Bladder Cancer 4:169-183(2018).
//
RX   PubMed=18812553; DOI=10.1093/jnci/djn304; PMCID=PMC2720731;
RA   Park, Hong-Seok
RA   Park, Weon Seo
RA   Bondaruk, Jolanta
RA   Tanaka, Noriyoshi
RA   Katayama, Hiroshi
RA   Lee, Sangkyou
RA   Spiess, Philippe Edouard
RA   Steinberg, Jordan R.
RA   Wang, Zhi
RA   Katz, Ruth L.
RA   Dinney, Colin Padraic Neal
RA   Elias, Keren J.
RA   Lotan, Yair
RA   Naeem, Rizwan C.
RA   Baggerly, Keith
RA   Sen, Subrata
RA   Grossman, Herbert Barton
RA   Czerniak, Bogdan
RT   "Quantitation of Aurora kinase A gene copy number in urine sediments
RT   and bladder cancer detection.";
RL   J. Natl. Cancer Inst. 100:1401-1411(2008).
//
RX   PubMed=25997541; DOI=10.1186/s12864-015-1450-3; PMCID=PMC4470036;
RA   Earl, Julie
RA   Rico, Daniel
RA   Carrillo-de-Santa-Pau, Enrique
RA   Rodriguez-Santiago, Benjamin
RA   Mendez-Pertuz, Marinela
RA   Auer, Herbert
RA   Gomez, Gonzalo
RA   Grossman, Herbert Barton
RA   Pisano, David G.
RA   Schulz, Wolfgang Arthur
RA   Perez-Jurado, Luis A.
RA   Carrato, Alfredo
RA   Theodorescu, Dan
RA   Chanock, Stephen Jacob
RA   Valencia, Alfonso
RA   Real, Francisco X.
RT   "The UBC-40 Urothelial Bladder Cancer cell line index: a genomic
RT   resource for functional studies.";
RL   BMC Genomics 16:403.1-403.16(2015).
//