ID   UM-RC-3
AC   CVCL_2740
SY   UMRC-3; UMRC3; University of Michigan-Renal Carcinoma-3
DR   cancercelllines; CVCL_2740
DR   CancerTools; 160447
DR   Cosmic; 972911
DR   DepMap; ACH-001687
DR   ECACC; 08090512
DR   PRIDE; PXD003105
DR   Wikidata; Q54990784
DR   Ximbio; 160447
RX   PubMed=4038766;
RX   PubMed=7915601;
RX   PubMed=26972028;
RX   PubMed=27141528;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: ~29 hours (PubMed=4038766).
CC   Sequence variation: Mutation; HGNC; HGNC:12687; VHL; Simple; p.Leu89His (c.266T>A); ClinVar=VCV000376047; Zygosity=Unspecified (PubMed=7915601).
CC   Omics: Proteomics; PTM; GPI-anchored proteins.
CC   Discontinued: ECACC; 08090512; true.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): DepMap=ACH-001687; ECACC=08090512
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9,12
ST   D16S539: 9
ST   D18S51: 13,15
ST   D21S11: 30.2
ST   D3S1358: 18
ST   D5S818: 9,12
ST   D7S820: 9
ST   D8S1179: 12
ST   FGA: 22
ST   Penta D: 13
ST   Penta E: 11,13
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16,18
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   PubMed=4038766; DOI=10.1002/jso.2930280320;
RA   Grossman H.B., Wedemeyer G., Ren L.-Q.;
RT   "Human renal carcinoma: characterization of five new cell lines.";
RL   J. Surg. Oncol. 28:237-244(1985).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008;
RA   Masuishi Y., Kimura Y., Arakawa N., Hirano H.;
RT   "Identification of glycosylphosphatidylinositol-anchored proteins and
RT   omega-sites using TiO2-based affinity purification followed by
RT   hydrogen fluoride treatment.";
RL   J. Proteomics 139:77-83(2016).
//
RX   PubMed=27141528; DOI=10.1016/j.dib.2016.04.001; PMCID=PMC4838930;
RA   Masuishi Y., Kimura Y., Arakawa N., Hirano H.;
RT   "Data for identification of GPI-anchored peptides and omega-sites in
RT   cancer cell lines.";
RL   Data Brief 7:1302-1305(2016).
//