ID   PEA-10
AC   CVCL_2684
SY   PEA 10; PEA10; Primary Embryonic Fibroblasts-10; LRP-1(+/-) MEF
DR   CLO; CLO_0008412
DR   CLDB; cl5105
DR   ATCC; CRL-2215
DR   ECACC; 97040310
DR   Wikidata; Q54946889
RX   PubMed=8006085;
CC   Knockout cell: Method=Homologous recombination; MGI; MGI:96828; Lrp1 (Note=1 of 2 alleles).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: C57BL/6 x 129.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   15FD
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 11
//
RX   PubMed=8006085; DOI=10.1242/jcs.107.3.719;
RA   Willnow, Thomas Erich
RA   Herz, Joachim
RT   "Genetic deficiency in low density lipoprotein receptor-related
RT   protein confers cellular resistance to Pseudomonas exotoxin A.
RT   Evidence that this protein is required for uptake and degradation of
RT   multiple ligands.";
RL   J. Cell Sci. 107:719-726(1994).
//