ID   MM603
AC   CVCL_2612
SY   MM 603
DR   BioSample; SAMN07624436
DR   cancercelllines; CVCL_2612
DR   CBA; CBA-1359
DR   Cosmic; 889032
DR   Cosmic; 928754
DR   ECACC; 11072801
DR   GEO; GSM170597
DR   GEO; GSM226730
DR   Progenetix; CVCL_2612
DR   Wikidata; Q54906181
RX   PubMed=9354451;
RX   PubMed=15048078;
RX   PubMed=17363583;
RX   PubMed=17516929;
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15048078; PubMed=17363583).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: Metastatic; Not specified.
ST   Source(s): CBA=CBA-1359
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 15
ST   D18S51: 12,13
ST   D19S433: 14
ST   D21S11: 29,30
ST   D2S1338: 17,19
ST   D3S1358: 14,15
ST   D5S818: 12,13
ST   D7S820: 11
ST   D8S1179: 12,17
ST   FGA: 20,23
ST   TH01: 8,9.3
ST   TPOX: 8,9
ST   vWA: 17,18
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 23
//
RX   PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152;
RA   Stark, Mitchell S.
RA   Hayward, Nicholas K.
RT   "Genome-wide loss of heterozygosity and copy number analysis in
RT   melanoma using high-density single-nucleotide polymorphism arrays.";
RL   Cancer Res. 67:2632-2642(2007).
//
RX   PubMed=15048078; DOI=10.1038/sj.onc.1207563;
RA   Pavey, Sandra
RA   Johansson, Peter
RA   Packer, Leisl
RA   Taylor, Jennifer
RA   Stark, Mitchell S.
RA   Pollock, Pamela M.
RA   Walker, Graeme J.
RA   Boyle, Glen M.
RA   Harper, Ursula
RA   Cozzi, Sarah-Jane
RA   Hansen, Katherine
RA   Yudt, Laura
RA   Schmidt, Chris
RA   Hersey, Peter
RA   Ellem, Kay Adrian Oswald
RA   O'Rourke, Michael G.E.
RA   Parsons, Peter G.
RA   Meltzer, Paul S.
RA   Ringner, Markus
RA   Hayward, Nicholas K.
RT   "Microarray expression profiling in melanoma reveals a BRAF mutation
RT   signature.";
RL   Oncogene 23:4060-4067(2004).
//
RX   PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x;
RA   Johansson, Peter
RA   Pavey, Sandra
RA   Hayward, Nicholas K.
RT   "Confirmation of a BRAF mutation-associated gene expression signature
RT   in melanoma.";
RL   Pigment Cell Res. 20:216-221(2007).
//
RX   PubMed=9354451;
RA   Castellano, Marina
RA   Pollock, Pamela M.
RA   Walters, Marilyn K.
RA   Sparrow, Louise E.
RA   Down, Louise M.
RA   Gabrielli, Brian G.
RA   Parsons, Peter G.
RA   Hayward, Nicholas K.
RT   "CDKN2A/p16 is inactivated in most melanoma cell lines.";
RL   Cancer Res. 57:4868-4875(1997).
//