ID   MM138
AC   CVCL_2602
SY   MM 138
DR   BioSample; SAMN07624423
DR   cancercelllines; CVCL_2602
DR   CBA; CBA-1345
DR   ECACC; 10092321
DR   GEO; GSM219445
DR   Progenetix; CVCL_2602
DR   Wikidata; Q54906046
RX   PubMed=294576;
RX   PubMed=460945;
RX   PubMed=1697409;
RX   PubMed=3756862;
RX   PubMed=17363583;
RX   PubMed=22383533;
CC   Doubling time: ~60 hours (ECACC=10092321).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=17363583).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=22383533).
CC   Omics: CNV analysis.
CC   Omics: SNP array analysis.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
ST   Source(s): CBA=CBA-1345
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 11
ST   D16S539: 10,12
ST   D18S51: 13,14
ST   D19S433: 14
ST   D21S11: 28,30
ST   D2S1338: 27
ST   D3S1358: 15,17
ST   D5S818: 11,12
ST   D7S820: 8,11
ST   D8S1179: 9,10
ST   FGA: 20,22.2
ST   TH01: 6
ST   TPOX: 11
ST   vWA: 16,19
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   32Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 20
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RX   PubMed=294576; DOI=10.3109/00313027909059039;
RA   Muir P.D., Gunz F.W.;
RT   "A cytogenetic study of eight human melanoma cell lines.";
RL   Pathology 11:597-606(1979).
//
RX   PubMed=460945; DOI=10.3109/00313027909061945;
RA   Pope J.H., Morrison L.E., Moss D.J., Parsons P.G., Dunne R.M.;
RT   "Human malignant melanoma cell lines.";
RL   Pathology 11:191-195(1979).
//
RX   PubMed=1697409;
RA   Chenevix-Trench G., Martin N.G., Ellem K.A.O.;
RT   "Gene expression in melanoma cell lines and cultured melanocytes:
RT   correlation between levels of c-src-1, c-myc and p53.";
RL   Oncogene 5:1187-1193(1990).
//
RX   PubMed=3756862;
RA   Maynard K., Parsons P.G.;
RT   "Cross-sensitivity of methylating agents, hydroxyurea, and
RT   methotrexate in human tumor cells of the Mer- phenotype.";
RL   Cancer Res. 46:5009-5013(1986).
//
RX   PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152;
RA   Stark M.S., Hayward N.K.;
RT   "Genome-wide loss of heterozygosity and copy number analysis in
RT   melanoma using high-density single-nucleotide polymorphism arrays.";
RL   Cancer Res. 67:2632-2642(2007).
//
RX   PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676;
RA   Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V.,
RA   Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M.,
RA   Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.;
RT   "A high-throughput panel for identifying clinically relevant mutation
RT   profiles in melanoma.";
RL   Mol. Cancer Ther. 11:888-897(2012).
//